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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development and Characterization of a Preclinical Swine Model of Osteogenesis Imperfecta

    SBC: Recombinetics, Inc.            Topic: NIDCR

    PROJECT SUMMARY Osteogenesis imperfectaOIalso known asbrittle bone diseaseis a genetic disease in which patients have defects in the formationstructureor strength of their bonescausing them to break easilyOI patients exhibit impaired tissue development and bone regeneration due to inherited mutations in one of the collagen genesleading to skeletal defectsbone fragilitydentinogenesis imperfectahear ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Gra

    SBC: ASTER LABS, INC            Topic: NCBDDD

    Abstract In this Phase II SBIR project, ASTER Labs will enhance a hands-free automatic oral hygiene device in the form of a comfortable mouthpiece that was designed and successfully tested and evaluated during a Phase I study for persons with oral hygiene disabilities and their caregivers, and then investigate the device’s efficacy in reducing dental plaque and reducing burden, thereby improving ...

    SBIR Phase II 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. Perfusion decellularization and recellularization for the creation of a bioengineered transplantable liver

    SBC: Miromatrix Medical Inc.            Topic: 300

    ABSTRACT Liver transplantation currently represents the only treatment for end stage liver disease (ESLD), the 8th most frequent cause of death in the United States (US). Efforts to overcome the chronic shortage of transplantable human livers include attempts at alternative organ procurement and replacement strategies. The most promising approach to date that provides the appropriate matrix compos ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Social Assistive Robot Interface for People with Alzheimer's and Other Dementias to Aid in Care Management

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    Project Summary Abstract Advanced Medical Electronics Corporation and our partners propose to develop a Socially Assistive RobotSARsystem for persons with dementiaPWDmild cognitive impairmentAlzheimerandapos s diseaseor other dementiaswho are living in assisted living facilitiesThe proposed system uses Augmented IntelligenceAIto communicate with the PWD in natural languageThe systemandapos s goals ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Bariatric Mannequin System to Enable Realistic Examination Simulations of Obese Patients

    SBC: Innovative Design Labs Inc.            Topic: 300

    Project Summary Abstract The proposed project focuses on creating a bariatric mannequin simulator to educate healthcare students on proper techniques specific and specialized to bariatric patient careSignificanceObesity is one of the world s most significant and growing health problemsMore thaninadults are overweight or have obesity and obese patients have a greater likelihood of requiring clinica ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Miniature Passive Device for Locating Lost Dentures in Care Facilities

    SBC: ASTER LABS, INC            Topic: NIDCR

    Abstract In this Phase II SBIR project ASTER Labs will significantly enhance an intuitive, safe, fully-embedded detection and localization solution for lost dentures. This concept was designed and successfully evaluated during Phase I with elderly denture wearers and caregivers, and tested for its accuracy and efficacy via demonstrations of successful localization of the misplaced prostheses in a ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors

    SBC: Vyriad, Inc.            Topic: 102

    PROJECT SUMMARY/ABSTRACT . Non-small cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC) are leading cause of cancer death globally. Immune checkpoint inhibitors (CPIs), which block tumor immune-evasion signals and activate T-cell mediated antitumor immunity, have demonstrated clinical efficacy and are approved for several cancers including NSCLC and HCC. Despite this broad spectrum of act ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Mixed Reality System for STEM Education and the promotion of health-related careers

    SBC: Innovative Design Labs Inc.            Topic: 400

    Project Summary/Abstract Proposed is a system to combine and leverage the advantages of existing medical props with interactive media to provide engaging and cooperative group STEM learning experiences. Significance: The PowerPoint lecture style has become the standard method for teaching groups of students. Unfortunately, this style does not emphasize student-instructor or student-student instruc ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    This project will develop a Socially-Assistive Robot (SAR) to provide cognitive training, in the form of learning to play the piano, to improve cognitive functioning and reduce feelings of loneliness in socially-isolated older adults. The SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functions: memory, at ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Automated Social Interactive Interface to Monitor and Update Intervention Plans for People with MCI, Alzheimer'sand Other Dementias

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    This fast track SBIR application submitted by Advanced Medical Electronics Corp. requests funds to develop a software system that helps people living with mild cognitive impairment, Alzheimer’s disease, and other dementia to age in place and give them the choice whether and when to move. Staying at home is both preferred and less expensive, but there are a number of challenges to overcome. The p ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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