Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. IGF OT IGF "SBIR PHASE I NEW D HUBIOGEL CULTURE SYSTEM FOR CANCER STEM CELLS EXPANSION and ANALYSIS"

    SBC: Vivo Biosciences Inc            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. IGF OT IGF VIVO BIOSCIENCES INC

    SBC: Vivo Biosciences Inc            Topic: NCI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Macromolecule Crystallization Screening Results Analysis

    SBC: IXPRESSGENES, INC.            Topic: 100

    DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Mapping electrogram morphology recurrence for atrial fibrillation ablation

    SBC: Gold T-Tech, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Atrial fibrillation AF is the most common diagnosed arrhythmia with the number Americans diagnosed with AF estimated at million and continuing to increase as the population ages Electrical activity during AF is characterized by complex activation patterns that are difficult to map However there is growing evidence that AF is driven by stable sources i ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Novel Membrane Protein Solubilization/Stabilization Screen

    SBC: SOLUBLE THERAPEUTICS, INC            Topic: 100

    DESCRIPTION provided by applicant The increasing output of new integral membrane protein IMP structures is partially due to the availability of an increasing number of chemical variables such as detergents detergent like molecules lipids and solubilizing stabilizing additives It is clear that specific combinations and concentrations of these different variables are often necessary to impr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A novel biomarker of infection in neutropenic cancer patients

    SBC: BIOPOWERTECH            Topic: NIAID

    DESCRIPTION provided by applicant Early diagnosis of an infection in neutropenic cancer patients is critical for timely treatment But the diagnosis of an infection in these patients especially at an early stage can be very challenging Therefore there is a great need for sensitive biomarkers that can rapidly predict an infection and provide possible outcomes We have already reported that s ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A novel phosphodiesterase isozyme target and class of inhibitors for lung cancer

    SBC: ADT Pharmaceuticals, LLC            Topic: 102

    DESCRIPTION provided by applicant Lung cancer causes more deaths in men and women than any other cancer in the United States Late detection of disease and inability to effectively treat this malignancy with chemotherapy are the main reasons for low survival rates There is an urgent medical need to develop new molecularly targeted drugs for treating lung cancer although it has been challengin ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Retrieval and Bio-material-compatibility Analyses of Prototype Temporomandibular Joint Implants Following 12-month Study in Swine

    SBC: VISTA ENGINEERING, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant Millions of Americans suffer from the debilitating disease of temporomandibular joint TMJ disorder affecting their ability to eat talk and live their lives For the patients whose joints do not respond to basic treatments and continue to have long term problems a doctor may recommend to perform surgical procedures to correct underlying problems in the join ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Mitigating Taxol-Induced Neuropathy through Modulation of the NMDA Receptor

    SBC: Naurex, Inc            Topic: 102

    DESCRIPTION provided by applicant Taxol paclitaxel is the one of the most widely used chemotherapy agents and is a first line treatment for ovarian breast lung and colon cancer Despite its well documented anti cancer properties taxol is known to cause chemotherapy induced peripheral neuropathy CIPN CIPN affects approximately of all chemotherapy patients and the neuropathic ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Microdomain Thermal Perturbations for Enhanced Nucleation of Proteins

    SBC: DENOVX, LLC            Topic: 100

    DESCRIPTION provided by applicant The ability to crystallize proteins for structural biology remains quite challenging with realized protein crystallization structure determination success rates hovering around DeNovX is developing rationally designed nucleation surfaces and thermal methods that enhance success rates and reproducibility for crystallization of proteins and small molecule ph ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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