Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. "SCRUBLESS" AMPLIFIED ELECTRODES FOR BIOELECTRIC PICKUP

    SBC: Infoscitex Corporation            Topic: N/A

    THE GOAL OF THIS RESEARCH IS TO DETERMINE THE PRACTICALITY OF ADDING SUBMINIATURE AMPLIFIERS TO THE ELECTRODES USED FORAUDITORY BRAINSTEM RESPONSE (ABR) RECORDING IN ORDER TO REDUCE OR ELIMINATE THE NEED FOR SCRUBBING (OFTEN LACERATING) THE SKIN PRIOR TO ELECTRODE PLACEMENT. IF SUCCESSFUL, THE SAME AMPLIFIER SYSTEM SHOULD ALSO (1) PERMITMORE ACCURATE "ELECTROCOCHLEOGRAPHY" RECORDINGS IN FRONT OF T ...

    SBIR Phase I 1987 Department of Health and Human Services
  2. A novel biomarker of infection in neutropenic cancer patients

    SBC: BIOPOWERTECH            Topic: NIAID

    DESCRIPTION provided by applicant Early diagnosis of an infection in neutropenic cancer patients is critical for timely treatment But the diagnosis of an infection in these patients especially at an early stage can be very challenging Therefore there is a great need for sensitive biomarkers that can rapidly predict an infection and provide possible outcomes We have already reported that s ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A novel phosphodiesterase isozyme target and class of inhibitors for lung cancer

    SBC: ADT Pharmaceuticals, LLC            Topic: 102

    DESCRIPTION provided by applicant Lung cancer causes more deaths in men and women than any other cancer in the United States Late detection of disease and inability to effectively treat this malignancy with chemotherapy are the main reasons for low survival rates There is an urgent medical need to develop new molecularly targeted drugs for treating lung cancer although it has been challengin ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. A Proton Radiography System for Optimization of Proton Therapy

    SBC: ProtonVDA LLC            Topic: NCI

    DESCRIPTION provided by applicant Our goal is to commercialize a high performance low cost proton radiography system based on well established fast scintillator technology This system will produce images of patients in terms of proton stopping power by tracking individual protons before and after the patient and measuring the proton residual range after traversing the patient The design of o ...

    SBIR Phase I 2015 Department of Health and Human Services
  5. A digital brain-gut therapy platform for enhanced management of Irritable Bowel Syndrome

    SBC: METAME HEALTH,INC            Topic: R

    Project Summary Abstract Irritable Bowel Syndrome IBS is a chronic and costly digestive condition characterized by abdominal pain and altered bowel habits diarrhea constipation or mixed type IBS is a disorder of brain gut dysregulation including the amplification of normal gut signals at the level of the brain Yet most medical therapies for IBS to date have focused on symptom management and dietar ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced Multi-Modal Wearable Sensing for the Prediction of Pre-Term Labor

    SBC: Sonica LLC            Topic: NICHD

    Preterm birthPTBdelivery prior toweeks gestational ageaccounts forof all births and remains the leading cause of neonatal deathThe majority of PTB is preceded by spontaneous preterm laborPTLCurrentlythere is a major unmet need for methods to identify women at risk of PTL and provide an early warning system for potential interventionhome uterine monitoringHUMis one approach that has shown some prom ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. AFFINITY PURIFICATION OF PARAINFLUENZA VIRUS GLYCOPROTEINS

    SBC: MOLECULAR ENGINEERING CORP.            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services
  8. A multiscale computational tool to simulate the PK of orally-administered drugs in the human GI tract

    SBC: CFD Research Corporation            Topic: 400

    A multiscale computational tool to simulate the PK of orally administered drugs in the human GI tract Project Summary AbstractMost FDA approved drugs are administered orallydespite the complex process of oral drug absorption that is difficult to analyze experimentallyOral bioavailability is dependent on the interplay between multiple and simultaneous processes that are dependent on both the drug c ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. An intuitive analysis software solution for protein complex native massspectrometry data

    SBC: PROTEINACEOUS, INC.            Topic: 400

    ABSTRACT Native top down mass spectrometrynTDMSis a multi tiered tandem mass spectrometry technique able to characterize proteoforms and intact protein complexes in their native state and represents a potentially revolutionary technology still in theearly adoptersstage of the technology life cycleBy utilizing gentle sample preparation and analysis methodsnTDMS can provide a direct measure of the e ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Portable Device for Accurate Mouse Tail Vein Injection

    SBC: Technology Commercialization Partners LLC            Topic: OD

    PROJECT SUMMARYABSTRACT To datethe standard method to access a mouse tail vein is manual injectionbut its yield rate is poor in generalThis leads to multiple needle insertions associated with tissue damage and painBesidesfailure in tail vein injection leads to data lossand thereby more animals will be required to compensate itFinallythe dose variation induced by unreliable injection increases erro ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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