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Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

Project Summary Abstract Covalent drug discovery is gaining increasing interest and clinical successespecially for cancer and infectious diseasesAlthough old covalent drugs were discovered serendipitouslymodern covalent drug discovery takes a rational approachWhile chemical intuition and trial and error are helpfulthe discovery process can be signi cantly shortened by the knowledge of whether the ...

MICROBIOLOGICALLY DEFINED LABORATORY ANIMALS ARE REQUIRED FOR SOPHISTICATED BIOMEDICAL RESEARCH. SEROLOGICAL PROCEDURES ARE THE MOST FEASIBLE AND ECONOMICAL MEANS TO MONITOR THEIR HEALTH STATUS. TYZZER'S DISEASE IS ONE OF THEMORE INSIDIOUS DISEASES OF LABORATORY RODENTS AND RABBITS FOR WHICH A SEROLOGIC TEST PROCEDURE IS NOT AVAILABLE COMMERCIALLY. THE ELUSIVE FASTIDIOUS ETIOLOGIC AGENT, BACILLUS ...

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Project Summary Abstract Irritable Bowel Syndrome IBS is a chronic and costly digestive condition characterized by abdominal pain and altered bowel habits diarrhea constipation or mixed type IBS is a disorder of brain gut dysregulation including the amplification of normal gut signals at the level of the brain Yet most medical therapies for IBS to date have focused on symptom management and dietar ...

DESCRIPTION provided by applicant Falls are a leading cause of injuries and deaths among older adults OAs and will be an increasing public health concern given projections of future increases in the number of OAs in the US Fall detection and or surveillance systems are needed to enhance an OAandapos s confidence and independence and to facilitate rapid post fall responses This project wil ...

Preterm birthPTBdelivery prior toweeks gestational ageaccounts forof all births and remains the leading cause of neonatal deathThe majority of PTB is preceded by spontaneous preterm laborPTLCurrentlythere is a major unmet need for methods to identify women at risk of PTL and provide an early warning system for potential interventionhome uterine monitoringHUMis one approach that has shown some prom ...

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We propose to design and implement a high-throughput and energy-efficient FPGA-based hardware processor (accelerator) for the deployment of Convolutional Neural Network (CNN) architectures at real-time embedded and resource-bound environments that have low size, weight, power and cost (SWaP-C) requirements. CNNs have been shown tremendous success in vision-based object detection tasks. Two differe ...