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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. PERCUTANEOUS TREATMENT OF PERIPHERAL ARTERIAL OCCLUSIVE DISEASE WITH IMPLANTATION OF SERIAL, BALLOON-EXPANDABLE, PACLITAXEL-ELUTING RESORBABLE SCAFFOLDS (the Efemoral Device)

    SBC: Efemoral Medical, LLC            Topic: NHLBI

    Project Summary Abstract TITLEPERCUTANEOUS TREATMENT OF PERIPHERAL ARTERIAL OCCLUSIVE DISEASE WITH IMPLANTATION OF SERIALBALLOON EXPANDABLEPACLITAXEL ELUTING RESORBABLE SCAFFOLDSthe Efemoral DeviceAbstract Peripheral Arterial Occlusive DiseasePAODalso known as Peripheral Vascular Diseasepoor circulationorhardening of the arteriesis a worldwide plagueSymptomatic PAOD affects approximatelyof the pop ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A single dose long-acting non-addictive polymer conjugate formulation of buprenorphine that provides immediate and prolonged analgesia for post-operative pain

    SBC: SERINA THERAPEUTICS INC            Topic: NINDS

    PAProject Summary Abstract SERis a long acting polymer pro drug of buprenorphine that is being developed to treat postoperative pain following major surgeries such as bunionectomyabdominoplastythoracotomy and knee and hip surgerySERhas no biological activity by itselfbut when administered in vivo by subcutaneous injection it enters the vascular compartment where a plasma esterasebutyrylcholinester ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Implantable Microarray Probe for Real-Time Glutamate and GABA Detection

    SBC: ALCORIX CO            Topic: 999

    Project SummaryThere is an enormous need for the development of a new class of neurotransmitterNTsensors that are versatileselectivesensitive and reliable to allow investigation of the neurobiological mechanisms of behavior and disease symptomsThis STTR proposal will focus on implementing a novel microarray probe for in vivoreal time sensing of glutamateGLUand gamma aminobutyric acidGABAGLU and GA ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Improving the Pelvic Health of Women and Girls Through the Use of a Digital Coaching Platform

    SBC: Below Your Belt L3C            Topic: NICHD

    ABSTRACT More thanmillion women suffer from pelvic health disordersPHDsin the United Statesa number that is projected to nearly double byThese conditions cost the healthcare system billions annually and negatively affect educational and employment opportunitiesquality of lifeand fertility of patientsWhile studies suggest that PHDs can be managed and improved with educationpractitioners are often c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Development of effective in-office autologouscell therapy for osteoarthritis

    SBC: JOINTECHLABS INC            Topic: NIAMS

    PROJECT SUMMARY Osteoarthritis is today a major worldwide challenge for health systemsrepresenting the most common degenerative joint disorder and the leading cause of chronic disability among older adultsIn the U SaloneOA affectsmillion people and it represents a $billion economic burdenAvailable pharmacological treatments only provide symptomatic pain relief and fail to arrest the progressive de ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Next Generation, Low Cost Tracking System for Healthcare Process Validation (2)

    SBC: GAN CORPORATION            Topic: 600

    PROJECT SUMMARY Significance: Americaandapos;s health care system remains challenged by tens of billions of dollars of fraud and inefficiencies. Lost and stolen equipment cost about $4,000 per hospital bed, increasing to $8,000 when expenses incurred from out-of-place equipment are added. In addition, a 2017 report estimates $95 billion was lost to fraud, waste, abuse, and other improper payments ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Inhibitors of cANGPTL4 for Pancreatic Cancer Therapeutics

    SBC: CFD RESEARCH CORPORATION            Topic: 102

    This project seeks to develop inhibitors of a novel pancreatic ductal adenocarcinomaPDACprotein targetPDAC remains one of the deadliest cancers with an average survival ofmonths for non resectable tumorsCurrentlya major obstacle in PDAC treatment is that the cells rapidly exhibit resistance to existing untargeted treatment regimens leaving patients with no further optionsStudies indicate that inhi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Array Based Affinity Selection

    SBC: Tango Biosciences Inc.            Topic: 300

    Project Summary Funds are requested to apply technologies being developed in a current NIGMS award to generate recombinant antibody-like affinity reagents to the spike protein of the SARS-CoV-2 virus. As a proof-of-principle experiment, we have already isolated four fibronectin type III (FN3) monobodies that bind with low nanomolar affinity to the receptor binding domain (RBD) of the viral spike p ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Developing a peptide-based oral drug to prevent kidney stones

    SBC: Oxalo Therapeutics, Inc.            Topic: 400

    Project Summary/Abstract Kidney stones (KS) are highly prevalent, excruciating, and associated with long term complications of chronic kidney disease (CKD) and end stage renal disease (ESRD). They account for 1.3M ER visits and andgt;$10B of medical costs annually and have a striking recurrence rate of 50% in 5 years and up to 80% in 10 years, reflecting the inadequacies of current interventions. ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. First and Only Soft Tissue Support Device to Improve Patient Experience and System Cost in Breast Reconstruction

    SBC: Surgical Innovation Associates, Inc.            Topic: 102

    NOTE: These pages contain proprietary/privileged information. SIA requests that they not be released to personsoutside the Government, except for purposes of review and evaluation. Project Summary/Abstract DuraSorb™ is poised to significantly improve the lives of the over 100,000 US women undergoing post- mastectomy breast reconstruction every year. The current standard of care in implant-based ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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