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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Discovery of Parasite-Derived Tolerogenic Adjuvants

    SBC: CELDARA MEDICAL, LLC            Topic: NIAID

    Our goal is to identify novel parasite derived immunomodulatory tolerogenic adjuvants that can suppress pro inflammatory and autoimmune disease statessuch as typediabeteswhich has no disease modifying treatmentParasitic helminths establish chronic infection by modulating host innate and adaptive immune responsesdown regulating T effector cellsstimulating Thand or inducing regulatory B and T cellsS ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Wearable Device for Objective Measurement of Opioid Withdrawal Symptoms in Newborns

    SBC: CREARE LLC            Topic: ODCDC

    More and more newborn babies are exposed to opioids in the womb and experience withdrawal symptoms at birthProperly diagnosing and treating patients is difficultnot all newborns that are at risk actually experience these withdrawal symptoms and require treatmentDiagnosis is affected by the experiencetrainingand opinion of the clinical staffBecause of the subjective nature of these assessmentssome ...

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. AUTOMATED PLATE TRANSPORT SYSTEM

    SBC: CREARE LLC            Topic: NIDA

    High throughput screeningHTShas emerged as a leading method of drug discovery and development in the pharmaceutical industryacademiaand at the NIH National Center for Advancing Translational SciencesNCATSHTS relies on the ability to rapidly screen tens of thousands of compounds to identify the most promising drugs and their dose response curvesHTS isof necessityhighly automated and demands mechani ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 343: NEUROPSYCHOLOGICAL ASSESSMENT SYSTEM FOR CANCER PATIENTS

    SBC: CREARE LLC            Topic: NCI

    Cognitive decline is a major quality of life concern for many cancer survivorsThevarious available treatments affect individuals differentlyand research has unfortunately provided little guidance on how specific treatments impact neurocognitive functionTo help researchers fill this information gap and ultimately provide guidance to doctors and patientsa neuropsychological assessment system that is ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A novel antibody therapy for Sin Nombre virus infection

    SBC: CELDARA MEDICAL, LLC            Topic: NIAID

    Project Summary Rodent-borne viral outbreaks are increasing in both frequency and impact. Hantaviruses are transmitted through the excreta of infected rodents and, when aerosolized, infect humans. In the Americas, hantavirus infection leads to hantavirus cardiopulmonary syndrome (HCPS), a devastating condition that features rapid onset of pulmonary edema, respiratory failure and cardiogenic shock. ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Micro-endoscopic impedance sensing for surgical margin assessment

    SBC: RYTEK MEDICAL INC            Topic: 102

    ABSTRACT The primary objective of surgical therapy for the treatment of patients with any cancer is to remove all cancer cells from within the bodywith the secondary objective of maintaining organ functionThe primary pathological metric used to rate the success of a surgical procedure is evaluation of the surgical margin of the resected tissue specimenpost operativelyThis typically involves cuttin ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. An unobtrusive monitoring device used for tracking asthma symptoms and lungfunction variability

    SBC: CLAIRWAYS LLC            Topic: NHLBI

    Executive Summary of Predicate (One Page) Summary of Specific Aims of Phase I Specific Aim 1: Train and evaluate an algorithm to detect pediatric asthma symptoms (cough and wheeze) on a low power, small form factor wearable device. Specifications: 90% sensitivity; false alarm rate: 1 cough episode/day or 1 wheeze episode/day. Evaluate algorithm against medical expert (physician) scoring using the ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Cellular Immunotherapy for Systemic Sclerosis

    SBC: CELDARA MEDICAL, LLC            Topic: NIAMS

    Project Summary Systemic sclerosis (SSc) is a systemic autoimmune disease that results in widespread fibrosis of the skin and internal organs, vascular dropout and autoantibody formation. SSc has the highest case fatality rate of any systemic autoimmune disease and there remain no FDA-approved therapies. Our data and that of others indicate that the innate immune system is the major driver of fibr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Reward-based technology to improve opioid use disorder treatment initiation after an ED visit

    SBC: Q2I, LLC            Topic: NIDA

    Project Summary Abstract Millions of people in the US misuse opioids each yearleading to thousands of deaths and costing billions of dollars in total economic burdenMedication assisted treatmentMATfor opioid use disorderOUDis highly efficaciousbut only a fraction of OUD persons access MATand treatment non adherence is common and associated with poor outcomesThis STTR Fast Track proposal is designe ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development/Commercialization of a Sensing Device to Detect Vaping

    SBC: FRESHAIR SENSOR, LLC            Topic: NIDA

    Development Commercialization of a Sensing Device to Detect Vaping Summary The use of e cigarettes or vaping has been steadily increasing since its introductionWhile potentially a tool to wean cigarette smokers from combustible tobaccoone consequence of the introduction of these devices has been the adoption of vaping by adolescentsWhile companies that offer vaping instruments for sale note that t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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