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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: XALLENT INC.            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Preclinical Development of Semisynthetic Saponin Immunological Adjuvant Titerquil-1055 in the Context of an Influenza Vaccine

    SBC: ADJUVANCE TECHNOLOGIES INC.            Topic: NIAID

    Increasingly defined vaccines against infectious diseases are better tolerated but less immunogenicrequiring use of an immunological adjuvant for best effectAdjuvance s semi synthetic saponin adjuvant TiterQuilTQLhas shown remarkable efficacy with a variety of antigens with no detectable reactogenicityWhen combined withof the leading vaccines against influenzaFluzoneFluarix and Flublokstriking aug ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Liposomal Platform for Spontageous, Particleized Presentation of HIV Trimer Immunogens

    SBC: POP Biotechnologies Inc.            Topic: NIAID

    Over one million Americans andmillion people worldwide are infected with HIVmaking it one of the most pressing public health concerns of our timeUnfortunatelythere are no vaccines available and treatment requires lifelong anti retroviral therapiesThis proposal combines two technologies for the development of a vaccine against HIVEnva novel adjuvantspontaneous nanoliposome antigen particleizationSN ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: LUCERNA INC            Topic: NCI

    Circular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmRNA trappingand protein translation regulationDeregulation in one or more of these roles has been linked to several types of cancerOne well studied circRNAciRSis believed to act as a miRNAsponge and in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR PHASE 1: SCALABLE DIGITAL DELIVERY OF EVIDENCE-BASED TRAINING FOR FAMILY TO MAXIMIZE TREATMENT ADMISSION RATES OF OPIOID USE DISORDER IN LOVED ONES.

    SBC: WE THE VILLAGE, INC.            Topic: NIDA

    The project goal is to develop digital delivery of Community Reinforcement and Family TrainingCRAFTmethodologyan empirical family behavioral intervention to improve outcomes around treatment entryfamily functioning and substance use

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Cardiac Monitor for VA ECMO Pediatric and Neonatal Patients

    SBC: TRANSONIC SYSTEMS, INC.            Topic: NHLBI

    7. PROJECT SUMMARY/ABSTRACT Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) is a way to provide cardiac and pulmonary support to patients without other alternatives. This form of life support is vital to pediatric and neonatal patients. As with any life support, there are serious complications that occur. These complications including bleeding, thrombosis, and infection become more freq ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Towards in vivo high-definition 3D corneal imaging

    SBC: LighTopTech Corp.            Topic: NEI

    The corneathe outermost window of our visual systemis vulnerable to various types of infections and diseasesCorneal disease is one of the leading causes of visual deficiency and blindness !There are nearlymillion bilaterally corneal blind persons worldwideand an estimatedmillion people affected by unilateral corneal blindness globallyIn a conservative estimatecorneal diseases affect nearlypeople i ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. An antigen-capture assay to screen donated blood for Babesia microti

    SBC: BIOPEPTIDES CORP            Topic: NIAID

    PROJECT SUMMARY In the U.S. ~5 million individuals receive blood transfusions annually. Increasingly, these recipients are being put at risk of infection with Babesia microti, a tick-transmitted blood-borne parasite that resides in red blood cells (RBCs) and causes the disease babesiosis. B. microti represents a significant threat to the US blood supply as it survives blood banking procedures and ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. New high-throughput screening technologies to improve cannabinoid production in yeast.

    SBC: LUCERNA INC            Topic: NCCIH

    SUMMARY Natural products derived from plants have played crucial roles in the treatments of many diseases throughout historyHoweverscarce natural sources and complex chemical synthesis have limited research and development and increased costs on these productsAn example of this is the non psychoactive cannabinoids found in cannabis plantsThere are overlow abundant cannabinoids that are known to be ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Automatic SUV Extraction and Biodistribution Analysis of Preclinical PET

    SBC: IN VIVO ANALYTICS, INC.            Topic: 100

    Preclinical positron emission tomographyPETplays a significant role in monitoring radiotracer biodistributions for the development of new therapiesThe standardized uptake valueSUVhas become one of the most important quantitation measures in PET analysisHoweverSUV extraction from PET data hinges on the ability to clearly delineate the organ region of interestROIfrom an anatomical referenceCross com ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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