Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigminebromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it actsas a temporary inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitigating th ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Photoacoustic Gasses Optical Detector and AnalyzerPhotoacoustic Gasses Optical Detector and Analyzer

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD171004

    To address the CBDs need for real-time analytical technology for multicomponent vapor identification and quantification, Physical OpticsCorporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA)autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In thePha ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Oxygen Isotope and Carbon Dioxide Analyzer for Measurements of Respiratory Quotients and Mechanisms in Soil and Dissolved Gases

    SBC: Nikira Labs Inc.            Topic: 24b

    DOE manages one of the largest groundwater and soil remediation efforts in the world and is responsible for the remediation of 6.5 trillion liters of contaminated ground water and 40 million cubic meters of contaminated soil generated at over 7000 discrete sites. These efforts often involve bioremediation, in which substances are injected into the subsurface to enhance microbial decomposition, and ...

    SBIR Phase I 2019 Department of Energy
  4. CryoSheet Jet¿: A Novel Vitrification Method for Biological Specimens

    SBC: Neptune Fluid Flow Systems LLC.            Topic: 26a

    With advances in detector technology and software algorithms, single-particle cryo- electron microscopy (cryo-EM) has taken the structural biology field by storm in the past five years. As the demand for three-dimensional reconstruction of biomacromolecules grows exponentially in both the academic and industrial sectors, technology features such as high throughput, high resolution, and automation ...

    SBIR Phase I 2019 Department of Energy
  5. Transparent, High-Resolution, Real-time X-ray Beam Imaging System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: 13a

    Fundamental research is ongoing to support missions in energy, environment, and national security and, particularly, to provide foundations for new energy technologies and materials and chemical characterization through X-rays. Diffraction-limited synchrotron light sources will increase the coherent X-ray flux (up to a few orders of magnitude) and brilliance. Many beamlines can dynamically change ...

    SBIR Phase I 2019 Department of Energy
  6. Radiation Hard Pixel Tracking Sensor for High Luminosity Colliders

    SBC: Sensor Creations, Inc.            Topic: 29c

    In this project we are proposing to develop a radiation hard monolithic active pixel sensor (MAPS) for MIPS tracking in high luminosity Nuclear Physics particle detectors. The performance is estimated to nearly match that of state of the art hybrid sensors. The device will be able to support very high hit rates of 750 MHz/cm2. These devices are suited to cover very large areas very close to the ve ...

    SBIR Phase I 2019 Department of Energy
  7. Low Temperature Thermionic Electron Source With Narrow Energy Spread

    SBC: Spark Thermionics, Inc.            Topic: 15c

    A major challenge in the field of electron microscopy is to reach energy resolution as low as 1 meV, which would improve the performance of currently used technologies and facilitate the development of novel techniques. The main roadblock limiting these developments are the currently available electron sources, which can only achieve resolution of 10 meV, an achievement that is already linked to m ...

    SBIR Phase I 2019 Department of Energy
  8. MULTI-MODED MULTI-FREQUENCY FAST SINGLE BUNCH BEAM DIAGNOSTIC INSTRUMENT

    SBC: TIBARAY, INC.            Topic: 09a

    Statement of Problem: Although beam control is critical to the optimal operation of accelerators, both for the large systems that exists in national and international laboratories and for industrial and medical accelerators, it is compromised by the high costs of diagnostic detectors and the need for information from multiple detectors to generate a complete picture of what is happening to the bea ...

    SBIR Phase I 2019 Department of Energy
  9. Development of Efficient Catalytic HBr Oxidation to Enable a Commercially Feasible Butane to Butenes Conversion Process

    SBC: Reaction 35, LLC            Topic: 22a

    The boom in shale gas development has caused US ethylene producers to shift to ethane feedstock, which has dramatically reduced the amount of higher hydrocarbon co-products, such as C3 and C4 olefins, that are themselves important feedstocks for derivative chemicals. In order to maintain productivity, chemical producers are interested in new technologies that can make these petrochemicals cost-eff ...

    SBIR Phase I 2019 Department of Energy
  10. Wide Field-of-View Dynamic Microlens Array Talbot Fluorescence Microscope for Bioimaging

    SBC: Intellisense Systems, Inc.            Topic: 27a

    The science of mesoscale to molecules bioimaging is being developed by creating novel multifunctional technologies to image, measure, and model key metabolic processes within and among microbial cells and multicellular plant tissues. Specifically, for efficient plant biomass- based biofuel production new bioimaging devices are sought for nondestructive, functional metabolic imaging of plant and mi ...

    SBIR Phase I 2019 Department of Energy
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