Award Data

Fullmoon has the first chip-level sensors capable of identifying and quantifying molecules in the air. At the core of our technology are printed voltammetric sensors, which are operated using cyclic voltammetry, an electrochemical technique that probes for the redox potential, a unique signature of molecules. We have demonstrated this sensing principle for the detection of carbon monoxide and meth ...

Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

This project is devoted to development of a manufacturing technique of slow neutron Germanium mosaic monochromators with reflectivity exceeding reflectivity of pyrolytic graphite crystals. The manufacturing technique utilizes optimized high temperature plastic deformation of large single Germanium crystals to produce mosaic monochromators. Preliminary test on 70 mm diameter Ge samples with 111 ori ...

Nodexus is commercializing next-generation bioinstrumentation for researchers, clinicians, and the biotech industry at large. As development challenge involves a material switch to polymer-based microfluidics to improve robustness and reproducibility of measurements. Nodexus will develop new manufacturing processes for their microfluidic product suite that preserves surface functionalization while ...

This Automated Access Control Policy Testing System (A-ACPTS) project extends and transitions NIST’s Access Control Policy Tool (ACPT) toward commercialization. The core challenge is to research and develop an ACPT-based tool and a method of automating as many of the inputs into the model checking as possible, with the goal of making the testing more usable, less error-prone, and more efficient ...

Promia will integrate the technology described in U.S. Patent #8,566,269 (Interactive Analysis of Attack Graphs (IAAG) Using Relational Queries) into the Promia Raven Security Information and Event Management (SIEM) and security operations appliance. Promia intends to use the asset information that it already collects – both passively and actively – about nodes on the networks it monitors and ...

We propose to demonstrate near infrared (NIR) InGaAs sensor arrays with 55% lower noise than arrays presently available to improve the sensitivity of current spectroscopy systems. The low noise performance will be enabled by the use of low-noise source follower per detector ROICs, which are also used in astronomy with HgCdTe for low noise measurements. With design improvements to current available ...

The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...