Award Data

Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

Microwave Applications Group designs and manufactures Radar Systems, subsystems and components for the Department of Defense by supplying to the primes. We have the capabilities to design and manufacture parts no longer supported by the original supplier by either building to print, requiring reverse engineering to develop replacements for materials that are no longer available, or reverse enginee ...

Volans-I operates a fleet of VTOL, autonomous logistics UAS, capable of autonomous navigation and delivery of mission critical supplies (20+ lbs) over the horizon and from distances in excess of 500 miles. Their systems are able to conduct fully autonomous deliveries in numerous austere conditions including moving target ship-to-ship operations as well as GPS and communications denied environments ...

Sierra Energy proposes to demonstrate the production of low-cost hydrogen from waste-derived syngas. Sierra is currently partnered with the DOD ESTCP Program, and the California Energy Commission (CEC) to build a pilot-scale gasification facility at the garrison at Fort Hunter Liggett (FHL) Syngas is a mixture of H2 and CO and can be used directly for the generation of electricity via a generat ...

Stratonics innovation is an in-situ thermal inspection system for additive manufacturing that monitors and identifies critical thermal indicators to significantly increase yield, reducing cost and schedule while correlating inspection data to post-process inspection, supporting certification and quality part production. In-situ inspection and analysis of key thermal metrics will reduce material wa ...

SDCs environmentally stable composite joint can be manufactured at costs on the order of steel equivalents, eliminate up to 98% of corrosion prevention costs, and provide an ROI greater than 10. SDCs ESC joint was demonstrated at TRL 4 to be structurally equivalent to comparable metal structures and to eliminate corrosive moisture ingress to critical regions of a structure. This DLA Phase I SBIR w ...

The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...

This proposal aims at solving for a “Computer-Assisted Strain Construction and Development Engineering (CASCADE)” (SBIR CBD06-107). Our approach is to integrate BioSpice (a DOD product) and our statistical model developed by Quantum Intelligence together with publicly available data to develop a system for discovering the predictive relations between genomic fingerprints of an organism and it ...