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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigminebromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it actsas a temporary inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitigating th ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Photoacoustic Gasses Optical Detector and AnalyzerPhotoacoustic Gasses Optical Detector and Analyzer

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD171004

    To address the CBDs need for real-time analytical technology for multicomponent vapor identification and quantification, Physical OpticsCorporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA)autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In thePha ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Handheld IR Raman Spectroscopy for Rapid Chemical Identification

    SBC: Aerius Photonics, LLC.            Topic: CBD08102

    Aerius Photonics and partner Ahura Scientific, propose to develop a handheld system, based on Ahura’s successful FirstDefender Raman system, that employs an excitation laser emitting at 980 nm and a low noise InGaAs array based on Aerius’ high performance InGaAs technology. This system will substantially reduce the fluorescence present in CCD-based systems, and unmask otherwise obscured spect ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: Los Gatos Research            Topic: CBD08104

    In this SBIR Phase I effort, Los Gatos Research (LGR) proposes to design, develop and test a novel laser-based gas analyzer optimized for chemical weapon exposure studies based on cavity enhanced absorption in the mid-infrared spectral region. This analyzer will provide sensitive and accurate quantification of several chemical weapons through real-time measurements of high-resolution absorption s ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Combined Dielectrophoretic Microfluidic System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD08101

    To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two-dimensio ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Respiratory Function Measurement System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD07112

    To address the CBD need for a real-time measurement system for nonhuman primate tidal volumes, suitable for a Class 3 biological safety (BSL-3) cabinet, Physical Optics Corporation (POC) proposes to develop a new Respiratory Function Measurement (RFM) system. This system is based on a piezoelectric strain transducer that responds to movement of an animal’s thoracic cage during respiration. The ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: GENOMATICA, INC.            Topic: CBD06107

    The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense
  8. Handheld Instrument for Nerve Agent Detection

    SBC: KUMETRIX, INC.            Topic: CBD06104

    Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense
  9. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: QUANTUM INTELLIGENCE, INC.            Topic: CBD06107

    This proposal aims at solving for a “Computer-Assisted Strain Construction and Development Engineering (CASCADE)” (SBIR CBD06-107). Our approach is to integrate BioSpice (a DOD product) and our statistical model developed by Quantum Intelligence together with publicly available data to develop a system for discovering the predictive relations between genomic fingerprints of an organism and it ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense
  10. Continuously Variable Attenuated-Phase-Shifted Photomask for Integrated Spectroscopic Sensor Platforms enabled by Optical Nanolithography

    SBC: Redondo Optics, Inc.            Topic: CBD05107

    Redondo Optics Inc. (ROI), a world leader in engineering and manufacturing of leading-edge nano-materials, optical sensors, fiber and integrated optics, and advanced photonics instrumentation proposes to develop and demonstrate for the first time the concept of an etch-less, deep-UV, fully continuously variable attenuated-phase-shifted mask (ConvaPSM™) technology to enable ultra-high resolution, ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense

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