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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigminebromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it actsas a temporary inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitigating th ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Photoacoustic Gasses Optical Detector and AnalyzerPhotoacoustic Gasses Optical Detector and Analyzer

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD171004

    To address the CBDs need for real-time analytical technology for multicomponent vapor identification and quantification, Physical OpticsCorporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA)autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In thePha ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Durable Anti-fog Coatings for Contoured Plastic Substrates Using Nanoparticles with Tunable Size and Surface Chemistry

    SBC: Innosense Llc            Topic: CBD09101

    Currently fielded respiratory protective systems in the Joint Services General Purpose Mask (JSGPM) program degrade in visual performance capability in extreme hot and cold environments. Optical and mechanical properties of existing anti-fog coatings also diminish when subjected to cleaning/sanitization operations. To address these needs, InnoSense LLC will develop durable anti-fog coatings that e ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  4. A Quarter Sized Optical NEMS Based Methyl Salicylate Detector

    SBC: IMAGINATIVE TECHNOLOGIES, LLC            Topic: CBD09103

    The objective of Imaginative Technologies, LLC teamed with Yale University is to design and build a “breadboard”, real time, optical NEMS Based Methyl Salicylate Detector (MSD), capable of measuring the presence and concentration of a chemical agent simulant (methyl salicylate – MeS) beneath a protective garment. This proposed device, MSD, will be the size of a quarter so it may be comfortab ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  5. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: Los Gatos Research            Topic: CBD08104

    In this SBIR Phase II program, Los Gatos Research (LGR) proposes to design, develop and test an advanced laser-based gas analyzer optimized for chemical weapon exposure studies based on cavity enhanced absorption in the mid-infrared spectral region. Building on the successful Phase I effort, this analyzer will provide sensitive and accurate quantification of several chemical weapons agents throug ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  6. Uncooled Imaging Spectrometer for Plume detection

    SBC: OPTO-KNOWLEDGE SYSTEMS, INC.            Topic: CBD09108

    Based on the CONOPS for gas plume detection, and the performance constraints of uncooled cameras, we propose to develop a dispersive scanning spectrometer, based on OKSI’s HyperScan and HyperSWIR family of scanning sensors. Not all uncooled cameras are equal, and not all exhibit the required characteristics for operating in spectral imaging systems under low flux environment. OKSI proposes to ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  7. Combined Dielectrophoretic Microfluidic System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD08101

    To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of gradient electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two ...

    SBIR Phase II 2009 Department of DefenseOffice for Chemical and Biological Defense
  8. Dielectrophoretic Microfluidic Protein Analysis System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD09104

    To address the U.S. Army CBD need for a low-cost, universal, robust, and fieldable device for rapid, reproducible identification of protein variants from biological samples with high throughput, Physical Optics Corporation (POC) proposes to develop a new Dielectrophoretic Microfluidic Protein Analysis (DiMiPA) system. The system is based on an electrodeless dielectrophoresis-based, continuous-flow ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  9. Bioweapon Identification and Triggering by Ionization Signatures

    SBC: SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES, INC.            Topic: CBD09109

    Modern bioweapon detection systems are highly accurate, but require expensive reagents to operate. To reduce costs, a less discriminate trigger system is used to signal the primary detector when a suspicious aerosol is present. Currently deployed UV fluorescence based trigger systems operate successfully, but only work with fluorescent bioweapons. An advanced technology is urgently needed to ad ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  10. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: GENOMATICA, INC.            Topic: CBD06107

    The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense

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