Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigminebromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it actsas a temporary inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitigating th ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Photoacoustic Gasses Optical Detector and AnalyzerPhotoacoustic Gasses Optical Detector and Analyzer

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD171004

    To address the CBDs need for real-time analytical technology for multicomponent vapor identification and quantification, Physical OpticsCorporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA)autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In thePha ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. A Personalized Wheelchair Fitting System to Improve Function and Quality of Life

    SBC: Kinetic Intelligence, LLC            Topic: NA

    The goal of this project is to confirm that informatics generated using the commercial version of the System for Personalizing and Evaluating the Fit of Assistive Devices in a Clinical Setting (SPEC) system, designed for clinicians by clinicians, can seamlessly integrate data into an Integrated Informatics System (IIS) database module for wheelchair fitting. The objectives are to: (1) verify that ...

    SBIR Phase I 2019 Department of Health and Human Services
  4. A point of care test for TB antibiotic concentration in blood

    SBC: NANOCOMPOSIX INC            Topic: NIAID

    TuberculosisTBis one of the topcauses of death worldwideTB treatments include combinations of multiple antibiotics and dosage levels over a long period of timeOften the dose must be adjustedLow antibiotic blood concentrations may cause slow responseprolonged infection or treatment failureand the TB strain may acquire drug resistancetoo high and toxicity may be an issueCurrent technologies for meas ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. POC Diagnostic for Gonorrhea and Determination of Antimicrobial Susceptibility

    SBC: Visby Medical, Inc.            Topic: NIAID

    VisbyFormally know as Click Diagnosticshas developed a PCR based rapiddisposablepoint of care test that automatically performs sample processingPCR amplificationand amplicon detectionLeveraging the existing platformClick willfrom a single urogenital sampledetect NG and determine whether the infecting strain is susceptible to three classes of antibioticsciprofloxacincefiximeor a novel antibiotic zo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. New Carriers Used as Adjuvants for Controlled HIV Immunogen Delivery into Targeted Antigen Presenting Cells

    SBC: NANOCOMPOSIX INC            Topic: NIAID

    Despite the global impacts of HIV on human healthwith an estimatedmillion new cases each year andmillion people living with HIVan effective vaccine has not been developedThere are many challenges for HIV vaccine development including the virus s rapidly changing surface immunogens and the early integration of the virus into the host s genomeTo overcome these challengesa mesoporous silica adjuvant ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Mobile Health Point-of-Care Diaagnostics for Malaria

    SBC: Chromologic LLC            Topic: NIAID

    A resurgence of malaria infections has occurred in the USprimarily due to increasing global travelOnly wide spread screenings and treatments of endemic populations can prevent the return of malaria endemicityCurrentlythere is no diagnostic test that meets the need of highly sensitive malaria screening tool for low resource settingsTo address this needChromoLogic proposes to develop the Quick Mag p ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Evaluation of VesiVax Adjuvant Formulations for HIV Vaccines

    SBC: Molecular Express Inc            Topic: NIAID

    This proposal aim to develop a VesiVaxplatform based liposomal vaccine that can co formulate the HIV antigenHIV Env gpAwith various immunotimulatory adjuvant moleculesIAMsThe IAMs that we will formulate with the antigen includeslipidated tucaresolmuramyl tripeptide phosphatidylethanolaminePam CAGmonophosphoryl lipid AdsRNAandcyclic dinucleotidesThe formulations will be evaluated in miceand selecte ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A smartphone-based point-of-care test for detection of influenza in low resource settings

    SBC: Luminostics, Inc.            Topic: NIAID

    Each yearinfluenza causes more thanhospitalizations and aboutdeaths in the U SPeriodicallypandemic strains of influenza emerge that cause even greater devastationthe most recent H Npandemic ofcausingdeaths in the U SDiagnostic testing for influenza is a critical component in managing the diseaseit offers data used in global influenza surveillance efforts and can help guide the treatment of individ ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Rapid Nucleic Acid Test for the Point of Care Detection of Malaria

    SBC: Crosslife Technologies Inc.            Topic: NIAID

    We propose the development of a highly sensitivesimple paper strip molecular nucleic acid blood test that detects parasites causing malaria at the point of careThe final product to be developed in Phaseis an FDA approved nucleic acid based diagnostic device paper dipstick test that contains a multiplex of probe that can amplify and detect nucleic acid sequences from the gametocyte specific pfstran ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government