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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TOPIC 369: NOVEL DOSING AND DISPENSING SYSTEM FOR MULTIPARTICULATE CANCER DRUGS

    SBC: HS-DESIGN, INC            Topic: NCI

    Oncology drugs continue to advance at a rapid pace with many therapies delivered orally as tablets or capsulesSmaller childrenhowevercannot swallow tablets or capsulesFor these drugs to be used in the pediatric population they need to be reformulatedTraditionally this has meant creating a liquid suspensionchewableor rapid dissolve tabletCancer medicationshoweveroften have terrible taste profiles t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Radiation Sterilizable, RFID Tagged Vials for Biomedical Samples

    SBC: BIOTILLION LLC            Topic: OD

    Abstract The Specific Aim of this Phase IIb (Phase II competitive renewal) SBIR proposal is to advance the prototypes we developed under our Phase I and II SBIR grants into commercial production. We will produce SBS-96 format radiation sterilizable electronically tagged sample vials that can be read at ultra-low temperatures. Hundreds of millions of SBS-96 vials are sold each year and each of thes ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Amorphous Pharmaceutical Product Development Using Containerless Methods

    SBC: MATERIALS DEVELOPMENT INC            Topic: 300

    Amorphous Pharmaceutical Product Development Using Containerless Methods Project Summary The overall objective of this research is to advance drug discovery through precise “engineering” of the structure and properties of API-bearing phases. Many emerging drugs cannot be used in their naturally insoluble crystalline forms or they require crystallization in a preferred polymorph in order to be ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Adenylyl Cyclase Type 5 Inhibition to Treat Myocardial Infarction

    SBC: VASADE BIOSCIENCES, INC.            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT The most significant advance in the treatment of Myocardial Infarction (MI) has been reperfusion therapy, which must be applied immediately after the MI diagnosis has been made. Despite the thousands of studies on drug therapies designed to reduce the size of the MI, most have failed in clinical trials. Our hypothesis is that a major reason why these drugs failed is that t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Protein therapeutic to facilitate healing of chronic wounds.

    SBC: TRIM-EDICINE INC            Topic: 300

    Project Summary This proposal builds upon the advances from the SBIR-Phase I program (R43GM123887), targeting the development of recombinant human MG53 (rhMG53), a novel tissue repair protein, as a topical therapeutic agent to facilitate healing of chronic wounds. Wound care represents a challenging problem to the public health, as no effective treatments for chronic non-healing wounds are availab ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Nucleation Enhanced Crystallization of Pharmaceuticals in Continuous Flow Manufacturing to Mitigate Therapeutic Drug Shortages

    SBC: DENOVX, LLC            Topic: 100

    PROJECT SUMMARY DeNovX and its collaborators in the Myerson Group at MIT are developing innovative approaches to improve crystallization of active pharmaceutical ingredients (APIs) and proteins. The goal of this Phase II grant is to expand the use of continuous flow crystallization using enhanced nucleation surfaces to the manufacture of small molecule therapeutics to improve efficiencies, economi ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Feasibility of a mobile parent-based intervention to reduce alcohol use by highschool seniors

    SBC: REAL PREVENTION LLC            Topic: 350

    The goal of this Phase II SBIR is to provide an efficient, engaging, and effective means to enhance parents’ ability to reduce prevalence of alcohol use and consequences, and other substance use through the development and evaluation of Parenting Now (PN). PN is a brief, interactive, self-paced, and digital curriculum for parents of high-school-aged adolescents, a frequently neglected population ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Cervix monitor for risk assessment of spontaneous preterm delivery

    SBC: ADVANCED TACTILE IMAGING INC            Topic: NICHD

    PROJECT SUMMARY Preterm delivery is a leading cause of infant mortality and morbidity. It is estimated that annually about 15 million infants are born preterm. Across 184 countries, the rate of preterm birth ranges from 5% to 18%. In most countries, the rate of preterm birth has risen in the recent decades, and now preterm birth represents the most common cause of neonatal mortality. It is the sec ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Wireless, implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary/Abstract Neuroscience research over the last decade has been revolutionized by many technological advancements. Pharmacology and optogenetics represent two distinct, and sometimes complementary tools used in neuroscience research to study the central and peripheral nervous systems in the context of the BRAIN initiative. Advanced interrogations of underlying neural circuits and biol ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. An Improved Method of Delivering a Sclerosing Agent for the Treatment of a Malignant Pleural Effusion.

    SBC: TDL INNOVATIONS LLC            Topic: 100

    Project Summary / Abstract. We are developing an improved clinical method to treat patients with malignant pleural effusions (MPE), a serious condition that occurs in 150,00-175,000 patients in the US each year, affecting between 7 to 15% of all cancer patients. MPE results in an excessive accumulation of liquid in the pleural cavity, frequently leaving the patient to suffer from shortness of brea ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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