Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. TOPIC 369: NOVEL DOSING AND DISPENSING SYSTEM FOR MULTIPARTICULATE CANCER DRUGS

    SBC: HS-DESIGN, INC            Topic: NCI

    Oncology drugs continue to advance at a rapid pace with many therapies delivered orally as tablets or capsulesSmaller childrenhowevercannot swallow tablets or capsulesFor these drugs to be used in the pediatric population they need to be reformulatedTraditionally this has meant creating a liquid suspensionchewableor rapid dissolve tabletCancer medicationshoweveroften have terrible taste profiles t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Biglycan as a Therapeutic for Muscular Dystrophy

    SBC: LIFECELL CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this proposal is to use animal models to test the efficacy of biglycan as a protein therapeutic for muscular dystrophy. Duchenne's muscular dystrophy (DMD) is a heritable disease that affects approximately 1 in 3,500 boys. These children are usually wheelchair-bound by age 12 and rarely survive past their early twenties. There are currently ...

    SBIR Phase II 2003 Department of Health and Human Services
  3. Performance Evaluation of a non-Degradable Synthetic Device for Chondral and Osteochondral Defects of the Knee

    SBC: Hydro-Gen LLC            Topic: NIAMS

    Injury to joints can lead to painful defects in articular cartilage and the underlying bonewhich adversely affect the function and biological health of the entire jointCurrent solutions for cartilagechondraland cartilage andboneosteochondraldefectsare unreliableare technically challengingand often require multiple proceduresA surgeon engineer biologist team at Hospital for Special SurgeryHSSdedica ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

    SBC: Prokaryotics, Inc.            Topic: NIAID

    Methicillin resistant Staphylococcus aureusMRSAand methicillin resistant Staphylococcus epidermidisMRSEare a major cause of bloodstream infections in the hospital and in the communityIndeedMRSA remains the second leading cause of mortality by drug resistant bacterial pathogens in the USAAlthough two mechanistically novel antibiotic classes exist to treat such infectionsDaptomycinDAP and LinezolidL ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria

    SBC: VisionQuest Biomedical Inc            Topic: NIAID

    Summary Cerebral malariaCMis a life threatening clinical syndrome associated with malarial infectionAnnuallymalaria affects more thanmillion people and claims the lives of overpeople worldwidemostly African childrenAs a consequence of the high incidence of CMit is often misdiagnosed for other pathologies with similar symptomsleading to a high false positive rate for CM and incorrect treatmentAn ac ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Next Generation Portable Power Amplifier

    SBC: MAXENTRIC TECHNOLOGIES, LLC            Topic: SOCOM13004

    MaXentric proposes the GAU2x2 wideband power amplifier system. The design combines MaXentrics wideband RF PA technology with advanced digital signal processing in a single small footprint package. This tight integration is made possible through the extremely high efficiency and low power dissipation. Since very little power is dissipated as heat, the package and heat sink size can be minimized. In ...

    SBIR Phase II 2019 Department of DefenseSpecial Operations Command
  7. Radiation Sterilizable, RFID Tagged Vials for Biomedical Samples

    SBC: Biotillion, LLC            Topic: OD

    Abstract The Specific Aim of this Phase IIbPhase II competitive renewalSBIR proposal is to advance the prototypes we developed under our Phase I and II SBIR grants into commercial productionWe will produce SBSformat radiation sterilizable electronically tagged sample vials that can be read at ultra low temperaturesHundreds of millions of SBSvials are sold each year and each of these vials must be ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Combining data types in meta analysis

    SBC: Biostatistical Programming Associates, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Over the past decade, meta analysis has come to play a key role in setting policy and also in planning new research. In gerontology, recent meta analyses have led to treatment recommendations or new insights in such areas as memory loss with normal aging, identifying, predicting, and treating Alzheimer's disease and dementia, depression in the elderly, percept ...

    SBIR Phase II 2003 Department of Health and Human Services
  9. Long-term therapeutic effects of synthetic bryostatin-1 in advanced AD without memantine

    SBC: Neurotrope Bioscience, Inc.            Topic: R

    Program Director Principal InvestigatorLastFirstMiddleMiao Kun Sun Project Summary Abstract The importance of memory impairment and dementiasincluding Alzheimer s diseaseADas a global priority has been well recognizedMany compounds that target AD pathologies have been developed preclinically but have failed in clinical trialsmostly for the lack of therapeutic efficaciesNeurotrope Bioscience Incis ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid and Effective Localized Neurovascular Cooling Using the Khione Insulative Catheter

    SBC: Tom L Merrill            Topic: 101

    Project Summary Stroke is theth leading cause of death and number one cause of adult disability in the United StatesThe primary goal of acute ischemic strokeAIStreatment is quickly restoring blood perfusionHoweverstudies have shown that this return of blood flowwhile necessarycan also cause damage to local tissue leading to poor patient outcomesTherapeutic hypothermiaTHhas been shown to be a robus ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government