Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Next Generation Portable Power Amplifier

    SBC: MAXENTRIC TECHNOLOGIES, LLC            Topic: SOCOM13004

    MaXentric proposes the GAU2x2 wideband power amplifier system. The design combines MaXentrics wideband RF PA technology with advanced digital signal processing in a single small footprint package. This tight integration is made possible through the extremely high efficiency and low power dissipation. Since very little power is dissipated as heat, the package and heat sink size can be minimized. In ...

    SBIR Phase II 2019 Department of DefenseSpecial Operations Command
  2. TOPIC 369: NOVEL DOSING AND DISPENSING SYSTEM FOR MULTIPARTICULATE CANCER DRUGS

    SBC: HS-DESIGN, INC            Topic: NCI

    Oncology drugs continue to advance at a rapid pace with many therapies delivered orally as tablets or capsulesSmaller childrenhowevercannot swallow tablets or capsulesFor these drugs to be used in the pediatric population they need to be reformulatedTraditionally this has meant creating a liquid suspensionchewableor rapid dissolve tabletCancer medicationshoweveroften have terrible taste profiles t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Radiation Sterilizable, RFID Tagged Vials for Biomedical Samples

    SBC: Biotillion, LLC            Topic: OD

    Abstract The Specific Aim of this Phase IIbPhase II competitive renewalSBIR proposal is to advance the prototypes we developed under our Phase I and II SBIR grants into commercial productionWe will produce SBSformat radiation sterilizable electronically tagged sample vials that can be read at ultra low temperaturesHundreds of millions of SBSvials are sold each year and each of these vials must be ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Amorphous Pharmaceutical Product Development Using Containerless Methods

    SBC: Materials Development, Inc.            Topic: 300

    Amorphous Pharmaceutical Product Development Using Containerless Methods Project Summary The overall objective of this research is to advance drug discovery through preciseengineeringof the structure and properties of API bearing phasesMany emerging drugs cannot be used in their naturally insoluble crystalline forms or they require crystallization in a preferred polymorph in order to be activeIn s ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Adenylyl Cyclase Type 5 Inhibition to Treat Myocardial Infarction

    SBC: VASADE BIOSCIENCES, INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT The most significant advance in the treatment of Myocardial InfarctionMIhas been reperfusion therapywhich must be applied immediately after the MI diagnosis has been madeDespite the thousands of studies on drug therapies designed to reduce the size of the MImost have failed in clinical trialsOur hypothesis is that a major reason why these drugs failed is that they must be ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Protein therapeutic to facilitate healing of chronic wounds.

    SBC: TRIM-EDICINE, INC.            Topic: 300

    Project Summary This proposal builds upon the advances from the SBIR Phase I programRGMtargeting the development of recombinant human MGrhMGa novel tissue repair proteinas a topical therapeutic agent to facilitate healing of chronic woundsWound care represents a challenging problem to the public healthas no effective treatments for chronic non healing wounds are availableMGis an essential componen ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Nucleation Enhanced Crystallization of Pharmaceuticals in Continuous Flow Manufacturing to Mitigate Therapeutic Drug Shortages

    SBC: DENOVX, LLC            Topic: 100

    PROJECT SUMMARY DeNovX and its collaborators in the Myerson Group at MIT are developing innovative approaches to improve crystallization of active pharmaceutical ingredientsAPIsand proteinsThe goal of this Phase II grant is to expand the use of continuous flow crystallization using enhanced nucleation surfaces to the manufacture of small molecule therapeutics to improve efficiencieseconomicsand dr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Feasibility of a mobile parent-based intervention to reduce alcohol use by highschool seniors

    SBC: Real Prevention LLC            Topic: 350

    The goal of this Phase II SBIR is to provide an efficientengagingand effective means to enhance parentsability to reduce prevalence of alcohol use and consequencesand other substance use through the development and evaluation of Parenting NowPNPN is a briefinteractiveself pacedand digital curriculum for parents of high school aged adolescentsa frequently neglected population created from the evide ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Cervix monitor for risk assessment of spontaneous preterm delivery

    SBC: Advanced Tactile Imaging, Inc.            Topic: NICHD

    PROJECT SUMMARY Preterm delivery is a leading cause of infant mortality and morbidityIt is estimated that annually aboutmillion infants are born pretermAcrosscountriesthe rate of preterm birth ranges fromtoIn most countriesthe rate of preterm birth has risen in the recent decadesand now preterm birth represents the most common cause of neonatal mortalityIt is the second largest direct cause of dea ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Wireless, implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary Abstract Neuroscience research over the last decade has been revolutionized by many technological advancementsPharmacology and optogenetics represent two distinctand sometimes complementary tools used in neuroscience research to study the central and peripheral nervous systems in the context of the BRAIN initiativeAdvanced interrogations of underlying neural circuits and biology ar ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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