Award Data

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

A personal air ventilation system (PAVS) can dramatically improve the environment inside chemical/biological protective clothing, protecting the health and safety of soldiers and enabling peak physical/mental performance for long periods. However, existing air blowers that can produce the flow rate and pressure drop needed for a PAVS are too heavy, inefficient, and noisy for a man-portable system ...

The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

This project develops software for hand held devices for use in elementary and secondarygrades. During Phase I of this project, Vcom3D developed and tested a prototype Mobile LanguageReference for students in the middle grades that included American Sign Language and Signed Englishdefinitions selected from the Signing Science Dictionary, developed by TERC and Vcom3D, aswell as explanations of mult ...

This project develops a wearable/portable robotic device, IntelliStretch, to perform therapeuticrehabilitation of the arm with the following three integrated steps: (1) stretching a spastic/stiff jointto its extreme position under intelligent control to loosen the stiff joint, (2) voluntary movement training using virtual reality games interfaced with assistance/resistance control when needed, and ...

Creates and evaluates a mobile version of a Signing Science Dictionary with at least 1,300 scientific terms

The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

This project combines 3D computer graphics and gaming technology to provide a nonlinear, immersive biology simulation ca lled OrganiSims. OrganiSims will be designed to convey highlevel biology concepts in a manner that engages high school students, and unify biology concepts while illustrating how these concepts interact. OrganiSims will enable students to observe and experiment with the key biol ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

A personal air ventilation system (PAVS) has the potential to dramatically improve the environment inside chemical/biological protective clothing. However, existing air blowers that can produce the flow rate and pressure drop required for a PAVS are too heavy and inefficient for use in a man-portable system. We propose to develop an innovative blower that can provide the required flow rate and p ...