Award Data

Develops a low-cost and portable rehabilitation device with intelligent control to stretch spastic joints safely and repeatedly througout the range of motion to reduce spasticity/contracture and increase functional performance

This project develops a wearable/portable robotic device, IntelliStretch, to perform therapeuticrehabilitation of the arm with the following three integrated steps: (1) stretching a spastic/stiff jointto its extreme position under intelligent control to loosen the stiff joint, (2) voluntary movement training using virtual reality games interfaced with assistance/resistance control when needed, and ...

Based on our successful experiences in automatic speech recognition, we propose a unique and promising solution for the automated objective speech intelligibility assessment system. It consists of a pair of head and torso simulators placed at the same distance as typical face-to-face communication, a power amplifier, a laptop computer, a speech recognizer, and console software. The simulator has a ...

Based on the success of our Phase I feasibility research, we propose to continue the project for the automated objective speech intelligibility assessment system. It consists of a pair of head and torso simulators placed at the same distance as typical face-to-face communication, a power amplifier, a laptop computer, a speech recognizer, and console software. The simulator has acoustic properties ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

The main objective will be to optimize the formulations developed and tested during the Phase I program for a high-performance, flexible, composite barrier that provides protection from Chemical, Biological, Radiological, and Nuclear agents and Toxic Industrial Materials. UDC will work toward the further improvement of chemical agent protection so that these flexible composite barriers will be ...

The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

A GROWING NATIONAL NEED EXISTS FOR COMPUTER WORK STATIONS WHICH INTEGRATE MANUAL DATA BASE PREPARATION FUNCTIONS FOR INCREASED ACCURACY, CONTROL AND PRODUCTIVITY. THESE WORK STATIONS COULD INCORPORATE DISABLED INDIVIDUALS SUFFERING FROM A VARIETY OF HANDICAPS INTO THE WORK PROCESS. THE RESEARCH IS DIRECTED TOWARD DEVELOPING BETTER USE OF COMPUTER TECHNOLOGY IN THE EDUCATION, TRAINING, AND PLACEMEN ...