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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ABSOLUTE NEAR-INFRARED BRAIN OXIMETER

    SBC: I.S.S (USA), Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goals in Phases I and II have been completed and showed the feasibility of our approach for assessing brain vascular autoregulatory responses to hypoxic stimuli. Frequency Domain Near-Infrared Spectroscopy offers the advantage of performing safe, non-invasive, transcranial, quantitative, real time measurements of cerebral hemodynamics and oxygenation. Our ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Absorbable and Low-Cost Radioseeds for Malignant Tumors

    SBC: XL Sci Tech Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase I research is to demonstrate the feasibility of creating timed-bioabsorbable Pd-103 seeds for the treatment of prostate tumors. Timed- bioabsorbable seeds have the combined benefits of titanium seeds, high dose rate temporary seeds, external beam radiation and other treatment options. In addition, timed-bioabsorbable seeds potentiall ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. A collaboration platform for proteomics biomarker analysis

    SBC: INSILICOS            Topic: N/A

    DESCRIPTION (provided by applicant): A novel computational analysis platform is proposed, which enables collaboration in the discovery and characterization of proteomics biomarkers. The proposed system is a broad academic-commercial collaboration, integrates several prominent proteomics efforts, and marks first major use in proteomics of virtual cluster technology. Consequently, the proposed platf ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. ADEPT GIS: ALCOHOL AND DRUG EPIDEMIOLOGY and TREATMENT GEOGRAPHIC INFORMATION SERVI

    SBC: LOOKING GLASS ANALYTICS, INC.            Topic: N/A

    This proposal describes enhancements to the ADEpT GIS, an internet-based software application that allows users to generate statistical analyses, maps, and reports on community-level measures of substance abuse. This web service augments the work of groups like the NIDA-sponsored Community Epidemiological Workgroups by providing a data repository and accessible analysis system for reporting and su ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. A Device to Enhance TENS Analgesic Effectiveness

    SBC: TALARIA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Heat produces analgesia through recognized physiologic mechanisms including stimulation of thermal receptors that inhibit nociception via the gate-control theory, by increasing blood flow, and by reducing muscular spasm. Similarly transcutaneous electrical nerve stimulators (TENS) reduce pain by electrically "blocking" pain impulses via gating of nociception. P ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Agonists of the RIG-I Innate Immune Pathway

    SBC: KINETA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a tremendous commercial demand for new antiviral products with novel mechanisms of action and which target a broad spectrum of viruses. Most previous and ongoing pharmaceutical development programs involve scre ening for inhibitors of essential virus enzymes with comparatively little investment in drugs that modulate the host immune response to infecti ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. AHL Hydrolase Mediated Biofilm Inhibition

    SBC: LYBRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bacterial biofilms thwart the control of nosocomial infections, such as those resulting from medical device implantation. Elevated levels of one or more quorum sensing (QS) signals have been linked to the formation of b acterial biofilms, which makes eradication of bacteria colonizing the growth-amenable surfaces of implants difficult due to their biofilm-media ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Airway Navigational System

    SBC: VIDA DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The detection of small nodules is possible given the emergence of high-resolution MDCT scanning, but often accurate diagnosis is delayed because a biopsy is not easily obtained. Thus, it is not possible to make the cancer diagnosis until rapid nodule growth is observed in subsequent follow up scans. This problem of finding nodules but delaying diagnosis and th ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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