Award Data

THIS PROPOSAL DESCRIBES THE DESIGN AND TESTING OF A NEW CLASS OF AMPEROMETRIC GLUCOSE SENSOR IN WHICH ELECTRICAL COMMUNICATION BETWEEN THE FLAVIN REDOX CENTERS OF GLUCOSE OXIDASE AND AN ELECTRODE IS ACHIEVED VIA A NETWORK OF DONOR-ACCEPTOR RELAYS CHEMICALLY BOUND TO A POLY(ETHYLENE OXIDE), OR PEO, BACKBONE. THESE POLYMERIC RELAY SYSTEMS COMBINE SEVERAL IMPORTANT FEATURES FOUND IN PREVIOUS POLYMERI ...

OUR OBJECTIVE IS TO DEVELOP AN APPROACH FOR COMMANDING MANUFACTURING MACHINES TO MOVE WITH GREATLY INCREASED DYNAMIC PERFORMANCE. THE PERFORMANCE INCREASE WILL BE ACHIEVED BY ELIMINATING EXCITATION OF OSCILLATIONS IN THE MACHINE. SETTLING TIME WILL, THEREFORE, BE SIGNIFICANTLY REDUCED. THE FEASIBILITY OF A NEW TECHNIQUE CALLED IMPULSE SHAPING WILL BE INVESTIGATED. A RUDIMENTARY VERSION OF IMPULSE ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

LEAD-BASED PAINTS ARE COMMONLY USED ON STEEL SUBSTRATES FOR OPACITY, REACTIVITY, DURABILITY, LUBRICATION, AND CORROSION PROTECTION PURPOSES. CONVENTIONAL SAND BLASTING METHODS FORREMOVAL OF SUCH PAINT COATINGS RESULT IN SIGNIFICANT ENVIRONMENTAL PROBLEMS AND ASSOCIATED DISPOSAL COSTS. PHASE I EFFORT IS DIRECTED TOWARD ESTABLISHMENT OF AN ALTERNATIVE TECHNIQUE NAMELY A LASER SYSTEM FOR PAINT REMOVA ...

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PLANT CELL CULTURES ARE A POTENTIAL SOURCE OF IMPORTANT SECONDARY METABOLITES SUCH AS MEDICINALS. CURRENTLY, LOW PRODUCTIVITIES HAVE IMPEDED COMMERCIALIZATION OF A BROADER RANGE OF TARGET COMPOUNDS. CELL IMMOBILIZATION COUPLED WITH CONTINUOUS REMOVAL OF SECRETED PRODUCTS HAS BEEN ADVOCATED AS A METHOD OF ENHANCING VOLUMETRIC PRODUCTIVITIES. RECENT ADVANCES SUGGEST THAT THE PREREQUISITE OF PRODUCT ...

FOR ELECTRONIC PACKAGING APPLICATIONS, THE THREE DESIRABLE PROPERTIES OF AN INSULATING CERAMIC SUBSTRATE ARE: HIGH THERMAL CONDUCTIVITY, THERMAL EXPANSION MATCH WITH THE DEVICE AND LOW DIELECTRIC CONSTANT. WHILE SOME MONOLITHIC CERAMICS SHOW PROMISE, AN ALTERNATIVE APPROACH IS TO DESIGN AND FABRICATE A COMPOSITE MATERIAL WHICH WILL HAVE THESE PROPERTIES. WE PROPOSE A NEW MATERIAL: GLASS CERAMIC MA ...

IN THE PROPOSED WORK, FEASIBILITY OF DEVELOPING AND CHARACTERIZING A HIGHLY SENSITIVE FAR INFRARED DETECTOR, BEYOND 1 MICRON WAVELENGTH REGION, USING A HIGH TC SUPERCONDUCTING BI-CA-SR-CU-O MATERIAL, IS EXAMINED. THE DETECTION PRINCIPLE IS BASED ON THE FACT THAT INCIDENT INFRARED RADIATION PRODUCES A VOLTAGE SHIFT ACROSS THE JOSEPHSON JUNCTION, WHICH CAN SERVE AS A USEFUL DETECTOR OUTPUT. THUS IN ...

IN THE PROPOSED PROGRAM, FOR THE FIRST TIME, EPITAXIAL GROWTH OF THIN FILM OF HIGH TEMPERATURE BISMUTH-CALCIUM- STUNTIUM-COPPER-OXIDE SUPERCONDUCTOR ON SILICON SUBSTRATE AT LOW PROCESSING TEMPERATURE BY LASER INDUCED DEPOSITION, IS EXAMINED. THE FIRST MOST IMPORTANT STEP IN SUCCESSFUL APPLICATION OF THESE HIGHLY PROMISING MATERIALS IN MICRO-ELECTRONICS AND HYBRID OPTO-ELECTRONICS, IS THE FABRICATI ...