Award Data

CDJ Technologies is an additive manufacturing (AM) company with technology that enables rapid printing over large build volumes. Thisresultant production throughput is differentiating within the AM technology space and enables the adoption of AM technology to addresslimited production-runs. There exist many items where the ability to customize a single component of a system can add substantial val ...

Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...

Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

Complete human anatomy avatars have a broad role in advanced training environments, performance-related physiological modeling, and simulations for the purpose of designing protective armor. The overall goal of this project is to design and develop computer software and data structures for adding articulated joints and natural motions to USARIEMs static finite element avatars and to create a graph ...

Fabrico Technology, Dr. Sanchita Bhadra and Professor Andrew Ellington of the University of Texas at Austin, have successfully demonstrated the proof-of-concept of an unparalleled, first-in-class in-field nucleic acid diagnostic platform for distinction of viable from non-viable E. coli and coliforms in

Our goal is to provide the Department of Defense with a reliable, point-of-need diagnostic device that is field-deployable, appropriatelysensitive, and can be easily adapted for detection of a variety of biological targets that are of interest to the defense community. Phase I of thisproject was for the initial demonstration and development of our low-cost personal diagnostic platform (referred to ...