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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: LYNNTECH INC.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Critical Data Processing for Chemical Warfare Simulant Field Testing – Advanced Data Fusion

    SBC: Torch Technologies, Inc.            Topic: CBD05110

    In this Phase II SBIR project for the Army CBD, Torch Technologies of Huntsville, AL, will develop and demonstrate a fully operational prototype of its Advanced Chemical Release Evaluation System for fusing measurements of the concentration of clouds resulting from chemical releases. The ability to evaluate the performance of a stand-off detector during development depends on the ability to accura ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. FRET-Aptamer Assays & Handheld Reader for Nerve Agent Metabolites

    SBC: Operational Techologies Corporation            Topic: CBD06104

    Operational Technologies Corporation (OpTech) proposes to couple the speed and ultrasensitivity of one-step (“bind and detect”) fluorescence resonance energy transfer (FRET) detection with the high affinity and selectivity of DNA aptamers (surrogate antibodies) to detect the phosphonic acid derivative metabolites of organophosphorous nerve agents in urine, blood, and other body fluids. In Pha ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense
  8. Imidazenil: A Protective Agent Against Chemical Warfare Agents induced Status Epilepticus

    SBC: NEUPHARMA, INC.            Topic: CBD05116

    The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  9. Modularized Transliteration Engine based on DMS

    SBC: Semantic Designs Inc            Topic: NGA06001

    This SBIR project will define a means for specifying and executing multiple transliteration systems to map written words in scripts in a variety of natural languages into Latin scripts. The work will investigate the issues behind transliteration of place names. It will define a domain-specific language, TSL, in which a transliteration system can be coded in a format easily written, understood and ...

    SBIR Phase I 2006 Department of DefenseNational Geospatial-Intelligence Agency
  10. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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