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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A biodegradable ophthalmic drug delivery device
SBC: Notus Laboratories, Inc. Topic: N/ADESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...
SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
A Biodégradable and Biomimetic Xerogel for Periodontal Bone Regeneration
SBC: INNOVATIVE RESEARCH SOLUTIONS INC Topic: NIDCRDESCRIPTION provided by applicant Periodontal bone regeneration requires attention to a the need of a physical barrier to restrict the entry formation of fibro epithelial tissue b he cause of bone loss that is due to hostandapos s inflammatory response to pathological cause and not due to the causative pathogen directly so along with bone regeneration strategies the process also equally ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
ABSOLUTE NEAR-INFRARED BRAIN OXIMETER
SBC: I.S.S (USA), Inc. Topic: N/ADESCRIPTION (provided by applicant): Our goals in Phases I and II have been completed and showed the feasibility of our approach for assessing brain vascular autoregulatory responses to hypoxic stimuli. Frequency Domain Near-Infrared Spectroscopy offers the advantage of performing safe, non-invasive, transcranial, quantitative, real time measurements of cerebral hemodynamics and oxygenation. Our ...
SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health -
Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin
SBC: VAXIN INC. Topic: N/ADESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
Adenovirus vectored vaccines for Alzheimer's disease
SBC: VAXIN INC. Topic: N/ADESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
A DIAGNOSTIC TEST TO ASSESS RISK ASSOCIATED WITH ANDROGEN THERAPY
SBC: G AND H MEDICAL PRODUCTS INTERNATIONAL Topic: N/ADESCRIPTION (provided by applicant): The indications for androgen therapy has expanded such that today, androgens are used in both men and women, and in addition to their use in treating primary (or secondary) hypogonadism the potential benefit of increasing bone mineral density, inducing greater muscle mass and strength, enhancing sexual function, and improving mood. Androgens are also being cons ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Adiponectin Secretion Enhancer Synthetic Organic Drug Discovery and Development
SBC: DISCOVERYBIOMED, INC. Topic: 200DESCRIPTION provided by applicant DiscoveryBioMed Inc DBM completed recently Phase I SBIR funded goals milestones specific experimental aims and efforts to screen synthetic organic small molecules on immortalized and primary differentiated human adipocyte platforms and to validate the high throughput screening HTS based Drug Discovery output with a Critical Path of bioassays dete ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
ADULT HUMAN PROGENITOR CELLS FOR CARDIAC REGENERATION
SBC: KARDIA THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): This proposal is the Phase II renewal of an STTR award to Kardia Therapeutics undertaken in collaboration with Baylor College of Medicine (the home to Kardia's founding scientists). The project will accelerate the development and commercialization of human heart-derived cardiac progenitor cells (CPCs), to promote more effective regenerative growth in human hear ...
STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health -
A Force-controlled Probe Based Platform for Single-Cell Biomolecular Delivery
SBC: INFINITESIMAL, LLC Topic: 100DESCRIPTION provided by applicant This proposed Phase II project will lead to a commercial product capable of transfecting individual target cells This new biotool uses a patented microfabricated chip called a nanofountain probe NFP to deliver molecules into live individual target cells by single cell electroporation which induces temporary nanopores in the cell membrane via the applicat ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
AHL Hydrolase Mediated Biofilm Inhibition
SBC: LYBRADYN, INC. Topic: N/ADESCRIPTION (provided by applicant): Bacterial biofilms thwart the control of nosocomial infections, such as those resulting from medical device implantation. Elevated levels of one or more quorum sensing (QS) signals have been linked to the formation of b acterial biofilms, which makes eradication of bacteria colonizing the growth-amenable surfaces of implants difficult due to their biofilm-media ...
SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health