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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A NANOeSPRi-based IVD Assay for Multiple Organ Injury

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHP14005

    Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  2. A Neck Injury Assessment Tool

    SBC: CFD RESEARCH CORPORATION            Topic: DHP13009

    The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  3. A Novel, Point-of-Care, Multi-Analysis Platelet Function Diagnostic System

    SBC: LYNNTECH INC.            Topic: DHP13013

    Platelets play a central role in hemostasis and are responsible for many inherited and acquired bleeding disorders and thrombic events in human beings. A significant portion of post-trauma deaths are related to coagulopathy or hemorrhage events for both injured soldiers and civilian patients. Several platelet function analyzers have been designed and developed; however due to form-factor and/or ...

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  4. Antimicrobial Protective Silicone and Carbon Based Wound Dressings

    SBC: LYNNTECH INC.            Topic: DHP13014

    Timely management and closure of burn wounds are critical for proper emergency care and the assurance of positive outcomes for the warfighter. Current technologies rely on reagents that cannot respond effectively to the different classes of pathogens that

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  5. A Point-of-Care Device for Diagnosis of Platelet Injury in Trauma Patients

    SBC: HEMOSONICS            Topic: DHP13013

    HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics device is based on sonorheome ...

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  6. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD RESEARCH CORPORATION            Topic: OSD11H14

    Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

    SBIR Phase II 2015 Department of DefenseDefense Health Agency
  7. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: LYNNTECH INC.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Burkholderia antibody molecules for therapeutics and diagnostics

    SBC: BIOO SCIENTIFIC CORPORATION            Topic: CBD14105

    Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram - negative bacteria and the causative agents of melioidosis and glanders, respectively. These infections, which occur in humans and other animals, are endemic is wide regions of the developing world. This Phase II SBIR project will build on the success of our Phase I work, which established methods for generating monoclon ...

    SBIR Phase II 2015 Department of DefenseOffice for Chemical and Biological Defense
  9. Camouflaged liposome construct for efficient drug delivery across the blood-brain barrier

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD08107

    A major obstacle to non-invasive treatment of brain injury and disease is the blood-brain barrier (BBB), which prevents many intravenously injected therapeutics from being taken into the brain. In this program, Luna Innovations and Virginia Tech propose to develop a novel liposome-based delivery system capable of delivering any of a variety of neuroprotective agents of use against organophosphate ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
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