Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Establishing Cavitation as a Damage Mechanism for Traumatic Brain Injury (TBI) from an Improvised Explosive Device (IED) Blast

    SBC: Advanced Technology And Research Corporation            Topic: SB082007

    The leading risk facing our soldiers in Iraq is an improvised explosive device (IED). IED attacks on vehicles create an extreme shock environment that has been linked to Traumatic Brain Injury (TBI). While the damage mechanisms that cause TBI remain elusive, several researchers have speculated that the damage mechanisms of stress and strain associated with non-war-related TBI may not sufficiently ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  3. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  4. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Hardware Independent Networked Active Sensor Middleware

    SBC: AID NETWORKS            Topic: SB082033

    The pioneering efforts within the DARPA SENSIT and NEST programs, proved the potential of wireless sensor network (WSN) technology for compelling DoD applications, including surveillance and target localization. These projects'' legacies include hardware platforms, used extensively in academic research today and the TinyOS software suite. At the same time, these programs revealed the limitations o ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  7. Effective Multi-core Software Development

    SBC: ALLOY COMPUTING, LLC            Topic: SB072010

    Multi-core processors pose a significant challenge for software application developers. This is because the vast majority of algorithms and applications have been - and continue to be - developed using methodologies and techniques that assume sequential runtime execution. The key to efficiently and effectively leveraging multi-core processors is the ability to expose, extract, and exploit concurr ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  8. Technological Advancements to the Simplified Automated Ventilator (SAVe II)

    SBC: AUTOMEDX, INC.            Topic: SB072006

    The proposed advancements of the SAVe ventilator will result in an easy to operate, small, lightweight, inexpensive, compressor-driven ventilator well suited not only to military applications and environments such as a battlefield (under the Tactical Combat Casualty Care doctrine), but civilian applications as well. The increased flow rate of a multiple pump design along with expanded control opt ...

    SBIR Phase I 2007 Department of DefenseDefense Advanced Research Projects Agency
  9. A High Level Synthesis Tool for FPGA Design from Software Binaries

    SBC: BINACHIP, INC.            Topic: SB062006

    Many DOD systems require advanced digital signal processing and image processing functions that cannot be efficiently implemented on conventional micro-processors, hence designers have started mapping these applications onto FPGAs. However, most FPGA implementations are manually designed and highly coupled to the hardware, often taking advantage of special hardware features of the target FPGA. T ...

    SBIR Phase I 2007 Department of DefenseDefense Advanced Research Projects Agency
  10. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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