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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Heterogeneous CB Sensor Network Modeling Tool

    SBC: ATMOSPHERIC & ENVIRONMENTAL RESEARCH, INC.            Topic: CBD07108

    While individual instances of Chemical/Biological (CB) detection sensor technology development have progressed steadily, deficiencies remain. An integrated multi-sensor network for CB detection is a promising concept for improving performance. New development is needed to address the complex challenge of how to optimally deploy and evaluate CB sensor networks to ensure maximum utility against an e ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  4. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Megapixel Uncooled Photomechanical LWIR Imager

    SBC: AGILTRON, INC.            Topic: SOCOM07005

    Agiltron has developed a breakthrough modular IR imaging technology that employs a photomechanical effect, in which an array of micro-machined sensor pixels converts IR radiation into visible light signals that can be optically detected by commercial off-the-shelf CMOS or CCD visible-light imagers. With commercial CMOS imagers achieving multi-megapixel resolution, the resolution of the modular Agi ...

    SBIR Phase I 2007 Department of DefenseSpecial Operations Command
  7. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Biologic Event Identification and Geolocation Unattended Ground Sensor

    SBC: STREAMLINE AUTOMATION LLC            Topic: SOCOM06018

    The DoD Chemical, Biological, Radiological, and Nuclear Defense Program Performance Plan discusses the status of sensing technologies and long-term goals, and shows point biological detection systems are expected to provide 20% of the objective capabilities in FY15. This indicates that there is the need for a man-portable, disposable, rapidly responding biological agent point detector that is cap ...

    SBIR Phase I 2007 Department of DefenseSpecial Operations Command
  9. Source Term Model for Fine Particles off Indoor Surfaces

    SBC: CAMBRIDGE ENVIRONMENTAL, INC.            Topic: CBD07109

    Computational fluid dynamics (CFD) is a powerful tool for predicting the dispersion of chemicals and biological (CB) agents in indoor environments. Unfortunately, techniques to specify CB emissions as input to CFD simulations lack in sophistication. Adequate models are not available for many important CB emission processes. Particle resuspension from surfaces, particularly relevant to CB agents ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  10. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
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