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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Digoxin Chiral Isolates as Improved Pharmaceuticals

    SBC: ACADEMIC PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): Digoxin is the first line pharmacologic therapy for CHF and AF. Digoxin increases cardiac contractility and blocks conduction through the AV node slowing the ventricular response to AF and thus slowing the rate of the beating ventricles permitting more time for the heart to fill. The recent Dig trial supports the use of digoxin in the treatment of CHF and the r ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. SBIR PHASE I, TOPIC 239 HIGH-THROUGHPUT SELECTION OF APTAMERS AGAINST CANCER BIOM

    SBC: Accacia International LLC            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Lightweight, Durable, Adjustable Composite Backrest

    SBC: ACCESSIBLE DESIGNS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We have designed a prototype lightweight, sturdy, user adjustable ergonomically designed backrest support for ultralight weight wheelchairs that will provide necessary postural support and provide a variety of positions to ease dressing, propulsion, and seated comfort. The backrest will improve user comfort, function, and posture during multiple activities of ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Novel Acoustic Resuscitation Monitor

    SBC: Active Signal Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently almost half of all trauma mortality is directly or indirectly attributable to hemorrhagic shock, accounting for more than 50,000 deaths yearly in the U.S. and hundreds of billions of dollars in economic costs. Active Signal Technologies proposes to develop an Acoustic Resuscitation Monitor (ARM) for enabling non-invasive assessment of systemic perfusi ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Compact sheath-flow-free multichannel flow cytometer

    SBC: Adeptas, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Flow cytometers are valuable tools for the rapid analysis of cells and macromolecules for both research and diagnostic purposes. Ideally, flow cytometry based analysis could benefit more researchers and clinicians if the units were more affordable, smaller, and even portable. New fabrication techniques and design approaches developed in the microfluidics and la ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Multi-frequency impedance sensor for cell analysis

    SBC: Adeptas, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Broadband impedance analysis of individual cells yields a wealth of information about cell size, viability, morphology and interior structure. Cell dielectric properties including membrane conductivity, cytoplasmic conductivity, and membrane capacitance can be derived from multi-frequency impedance data and used to differentiate and enumerate cell populations i ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Low Cost Automated Urinalysis using Spectral Data

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Clinical urinalysis is performed to examine the chemical and formed particle composition of urine. It is used as a screening and/or diagnostic tool to detect different metabolic and kidney disorders, urinary tract infections, diabetes and pregnancy. Routine urinalysis consists of a physical (color, clarity, odor), chemical (protein, glucose, nitrites, etc.), an ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Vascular Permeability Normalization in Ischemic Stroke

    SBC: Advanced Life Sciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the United States and is the number one cause of adult disability. It is estimated that this clinical condition results in a cost of $30-40 billion in the U.S alone. While a large number of therapeutic agents have been investigated for the treatment of ischemic stroke, only one agent is currently approved for marke ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Targeted Therapy for Breast Cancer

    SBC: A&G PHARMACEUTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer remains one of the top three cancers to affect and cause mortality in women. Major shortcomings with current treatment are the high level of side effects and insufficient efficacy, particularly for patients with metastatic disease. Targeted cancer therapy is designed to treat only the cancer cells and minimize damage to healthy cells. These target ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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