List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: Lynntech Inc.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Combined Dielectrophoretic Microfluidic System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD08101

    To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two-dimensio ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: GENOMATICA, INC.            Topic: CBD06107

    The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  6. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: QUANTUM INTELLIGENCE, INC.            Topic: CBD06107

    This proposal is to respond Army CBD SBIR Phase II invitation for “Computer-Assisted Strain Construction and Development Engineering (CASCADE)”. Our approach is to apply a machine learning system together with publicly available data and private collaboration data for discovering the predictive relations between genomic fingerprints of an organism and its metabolic capabilities, and then use t ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  8. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  9. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: Los Gatos Research            Topic: CBD08104

    In this SBIR Phase I effort, Los Gatos Research (LGR) proposes to design, develop and test a novel laser-based gas analyzer optimized for chemical weapon exposure studies based on cavity enhanced absorption in the mid-infrared spectral region. This analyzer will provide sensitive and accurate quantification of several chemical weapons through real-time measurements of high-resolution absorption s ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Handheld Instrument for Nerve Agent Detection

    SBC: KUMETRIX, INC.            Topic: CBD06104

    Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government