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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ABSOLUTE NEAR-INFRARED BRAIN OXIMETER

    SBC: I.S.S (USA), Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goals in Phases I and II have been completed and showed the feasibility of our approach for assessing brain vascular autoregulatory responses to hypoxic stimuli. Frequency Domain Near-Infrared Spectroscopy offers the advantage of performing safe, non-invasive, transcranial, quantitative, real time measurements of cerebral hemodynamics and oxygenation. Our ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. A Chaperonin/Osmolyte Protein Folding Screen- STTR Phase I

    SBC: EDGE BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One of the largest bottlenecks in high-throughput protein structure determination (structural genomics) and in subsequent drug targeting (pharmocogenomics) is the acquisition of soluble correctly folded functional protein products. Unfortunately, a large amount of the protein expression systems that are commonly used yield insoluble or soluble misfolded protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Add-on module for ONCAD for diagnosing infiltrating lobular carcinoma

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this study is to develop an add-on module for the ONCAD breast MRI CAD system that will provide radiologists with additional assistance when they have suspicion of the presence of infiltrating lobula r carcinoma (ILC). The proposed research will investigate the possibility of developing, training and evaluating an ILC- specific algorithm tha ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Adenovirus Vectors for Respiratory Syncytial Virus Vaccination

    SBC: GENVEC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the leading viral cause of lower respiratory illness and hospitalization in young children and has long been recognized as a priority disease for a vaccine. RSV presents many challen ges for vaccine efficacy. Over the nearly 40 years since the failed formalin-inactivated RSV vaccine great strides have been made in understand ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. A DIAGNOSTIC TEST TO ASSESS RISK ASSOCIATED WITH ANDROGEN THERAPY

    SBC: G AND H MEDICAL PRODUCTS INTERNATIONAL            Topic: N/A

    DESCRIPTION (provided by applicant): The indications for androgen therapy has expanded such that today, androgens are used in both men and women, and in addition to their use in treating primary (or secondary) hypogonadism the potential benefit of increasing bone mineral density, inducing greater muscle mass and strength, enhancing sexual function, and improving mood. Androgens are also being cons ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. ADULT HUMAN PROGENITOR CELLS FOR CARDIAC REGENERATION

    SBC: KARDIA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is the Phase II renewal of an STTR award to Kardia Therapeutics undertaken in collaboration with Baylor College of Medicine (the home to Kardia's founding scientists). The project will accelerate the development and commercialization of human heart-derived cardiac progenitor cells (CPCs), to promote more effective regenerative growth in human hear ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  9. AHL Hydrolase Mediated Biofilm Inhibition

    SBC: LYBRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Bacterial biofilms thwart the control of nosocomial infections, such as those resulting from medical device implantation. Elevated levels of one or more quorum sensing (QS) signals have been linked to the formation of b acterial biofilms, which makes eradication of bacteria colonizing the growth-amenable surfaces of implants difficult due to their biofilm-media ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Airway Navigational System

    SBC: VIDA DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The detection of small nodules is possible given the emergence of high-resolution MDCT scanning, but often accurate diagnosis is delayed because a biopsy is not easily obtained. Thus, it is not possible to make the cancer diagnosis until rapid nodule growth is observed in subsequent follow up scans. This problem of finding nodules but delaying diagnosis and th ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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