Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Development of a Fire-Resistant, Thermal Barrier Coating with Low-Temperature Flexibility

    SBC: Advanced Materials and Processes            Topic: A08T028

    Advanced Materials and Processes (AMP) can deliver a Thermal Barrier Coating (TBC) with low temperature flexibility. This is possible because of a major breakthrough in hollow clay nanotube technology. Halloysite nanotubes (HNT™) have been shown to increase coating flexibility an order of magnitude by reinforcing the binder at the nanolevel. HNT have been filled with liquid flame retardant (F ...

    STTR Phase I 2008 Department of DefenseArmy
  3. Cyclops

    SBC: Advanced Optical Systems, Inc            Topic: A08041

    The Army needs smaller and cheaper precision weapon systems. Semi-Active Laser guidance (SAL), invented in the 1960’s at the Army Missile command, is a powerful approach to smart weapons. In the past, SAL seekers used quadrant detectors, narrow field-of-view optics, gimbals, and actuators. While very effective, they are expensive. Several programs are desperate for a low-cost solution. One drivi ...

    SBIR Phase I 2008 Department of DefenseArmy
  4. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  5. Xenopus Melanophore-Based Toxicity Sensor for Water

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A07T030

    Deployed armed forces often have to rely on water that is produced from decentralized sources, which presents significant difficulties for assuring the water is free of chemical toxicants. Analysis of these water supplies often requires complex instrumentation that is not practical for field use. An innovative alternative is the use of cell-based biosensors that can rapidly assess the general to ...

    STTR Phase I 2007 Department of DefenseArmy
  6. Detection of Explosive Materials Using an Encapsulated Fluorescent Bioprobe

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A06T025

    The use of explosives over the last 100 years has left up to 16,000 military ranges contaminated with highly toxic compounds. A major challenge to the remediation of these ranges is identifying the location of persistent explosives residues. To meet this challenge, Agave BioSystems in collaboration with Universities Space Research Agency (USRA) is developing an encapsulated fluorescent bioprobe ...

    STTR Phase II 2007 Department of DefenseArmy
  7. Branched DNA Diagnostic for Malaria Parasites

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08118

    The key to effective management of malaria is accurate diagnosis that is also rapid. The “gold standard” microscopy is time-consuming and labor-intensive and suffers from retirement of microscopic diagnostic experts and inaccurate slide reading. A field-deployable diagnostic method that is specific for the different malaria parasites and is capable of quickly processing potential patients wo ...

    SBIR Phase I 2008 Department of DefenseArmy
  8. Ante-Mortem TSE Diagnosis by Electric Cell-Substrate Impedance Sensing

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T035

    Transmissible spongiform encephalopathies (TSE) are responsible for fatal neurodegenerative diseases in humans, cattle, and sheep/goats. As TSEs can take many months and even years to present clinical symptoms, it is critical for food and contact safety to diagnose the disease at the earliest possible time point. A cell culture based system can offer the sensitivity and specificity required for a ...

    STTR Phase I 2008 Department of DefenseArmy
  9. Xenopus Melanophore-Based Toxicity Sensor for Water

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A07T030

    Deployed armed forces often have to rely on water that is produced from decentralized sources, which presents significant difficulties for assuring the water is free of chemical toxicants. Analysis of these water supplies often requires complex instrumentation that is not practical for field use. An innovative alternative is the use of cell-based biosensors that can rapidly assess the general toxi ...

    STTR Phase II 2008 Department of DefenseArmy
  10. Cell-based High Throughput Screening of Compounds Improving Mitochondrial Energetics

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T006

    Improving age-related decrease in cognitive and physical capabilities has tremendous potential for the civilian population and military personnel, including prolonged aptitude of highly-trained military personnel and lowering of healthcare costs. Mitochondria, the organelle responsible for energy production in eukaryotic cells, are directly involved in programmed cell death and associated to the ...

    STTR Phase I 2008 Department of DefenseArmy
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