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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Rapid Detection of E.coli O157:H7, Salmonella spp. and Listeria spp.

    SBC: Advanced Analytical Technologies, Inc.            Topic: N/A

    Rapid tests for microbial detection in food processing on the market today provide information on the presence or absence of specific pathogens after an enrichment process of 24 to 48 hours. Our method will utilize immunomagnetic separation after brief enrichment (

    SBIR Phase I 2002 Department of Agriculture
  3. In-Soil Hatching and Propagation of Commercially Marketable Earthworm Cocoons

    SBC: Advanced Prairie, Inc.            Topic: N/A

    "The beneficial effects of earthworms on soil structure, chemistry, microbiology, and crop yield are well demonstrated. Advanced Prairie, Inc. has developed a method of harvesting and encapsulating earthworm cocoons to make them available for mass market distribution. A previous SBIR proposal demonstrated the storage (at least five months) and shipping viability of the encapsulated cocoons. The pr ...

    SBIR Phase I 2007 Department of Agriculture
  4. RNAi screening for Identification of Compounds to Induce Suspended Animation or Hypometabolism

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    While the phenomenon of suspended animation has not been widely studied in humans, there are many anecdotal and medically verified examples of humans being in a state that is comparable to suspended animation when they have been accidentally nearly frozenfor short periods of time. There could be many advantages to inducing suspended animation or hypometabolism in humans such as extending survival ...

    SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
  5. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  6. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Efficacy of Recombinant Redox Enzymes from Corn in Wood and Textile Applications

    SBC: Applied Biotechnology Institute, Inc.            Topic: N/A

    NON-TECHNICAL SUMMARY: Industrial proteins produced in plants, particularly corn, offer a unique opportunity for industrial scale production of enzymes at competitive prices and yields that will address markets that cannot be addressed today. These corn-produced enzymes open the possibility to address such large markets as pulp bleaching, textile bleaching, bio-glues and enzymatic remediation of w ...

    SBIR Phase I 2003 Department of Agriculture
  9. Cellulases for Biomass Conversion from the Transgenic Maize Production System

    SBC: Applied Biotechnology Institute, Inc.            Topic: N/A

    NON-TECHNICAL SUMMARY: The production of ethanol from lignocellulosic biomass can utilize large volumes of agricultural residues that are untapped today. Ethanol fuels burn cleanly, thus the use of ethanol for partial replacement of petroleum fuels will have a positive impact on the environment. The production of ethanol fuels from lignocellulosic biomass is ready to be developed into a viable ind ...

    SBIR Phase I 2003 Department of Agriculture
  10. Sustainable Production of Pinfish (Lagodon rhomboides) for the Live Bait Market

    SBC: AQUATIC INNOVATIONS            Topic: N/A

    Recreational saltwater fishing is a major industry in coastal areas of the United States. The U.S. Fish and Wildlife Service estimated that saltwater anglers spent $8.4 billion in 2001 on fishing trips and supplies. In many communities this type of "wildlife tourism" is the lifeblood of the community. It is vital to these communities to have a consistent supply of needed goods for these anglers. T ...

    SBIR Phase I 2008 Department of Agriculture
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