Award Data

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

Biological weapons are among the most serious threats facing the United States defense forces, today. Currently available bioaerosol sampling systems and cassettes require both sample preparation and a well equipped laboratory for analysis. Other detection methods rely on fragile bio-molecules for recognition of the target analyte. These systems are not suitable for onsite analysis. Infrared spec ...

While zero-based tolerance protective clothing is suitable for first responders, it provides an unnecessary level of protection for first receivers who are exposed to a considerably reduced threat. The use of zero-based tolerance garments by first receivers is particularly problematic since they often work in the same garments for an extended period of time. Consequently, the unique needs of fir ...

"The importance of DNA/RNA-based assays for detection of biological warfare agents, identification of diseases, genome sequencing, and environmental control is enormous and will inevitably increase. The challenge is the development of low cost andportable methods for sequencing DNA and RNA extracted from surfaces and fluids, to recognize exposure to biowarfare agents. All the conventional techn ...

The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

This SBIR Phase II project aims to develop a commercial grade optical probe and system for FDA clinical trials and subsequent commercialization of a population-wide colon cancer screening test. An interdisciplinary research team of engineers, biologists, and clinicians has developed low-coherence enhanced backscattering (LEBS), an optical technique which enables sensing tissue microarchitectural c ...

This Small Business Innovation Research Phase II project develops the manufacturing process for a cement additive from an agricultural biomass waste to be used in the production of High Performance Concrete (HPC), and blended cement. This additive imparts increased strength and durability to concrete; therefore will mostly be used in high-rise buildings, highway construction, and infrastructures ...

This Small Business Innovation Research (SBIR) Phase II project addresses the device and market opportunity for in-plane propagation of light in-planar anisotropy magnetic garnet films for high sensitivity, high speed magneto-optic sensors, switches and modulators. Traditional perpendicular propagation devices require perpendicular magnetic fields and magnetization processes. These are limited in ...

This Small Business Innovation Research (SBIR) Phase II project is developing an advanced questions answering (QA) system with the use of innovative natural language processing (NLP). The specific areas addressed by this project are: (1) a true open-domain, high precision QA system optimized for commercial deployment; (2) distributed processing that provides an unprecedented QU system response tim ...

The Small Business Innovation Research (SBIR) Phase II project will support the commercialization of a novel line of high-performance Mayacrom pigments using a lower cost, solid-state, environmentally friendly one-step manufacturing process. The Mayacrom pigments exhibit superior properties compared with many commercially available pigments and may replace environmentally detrimental pigments such ...