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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Reagentless and Realtime Detection of Airborne Microorganisms

    SBC: LYNNTECH INC.            Topic: CBD06102

    Biological weapons are among the most serious threats facing the United States defense forces, today. Currently available bioaerosol sampling systems and cassettes require both sample preparation and a well equipped laboratory for analysis. Other detection methods rely on fragile bio-molecules for recognition of the target analyte. These systems are not suitable for onsite analysis. Infrared spec ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Self-Detoxifying, Disposable Protective Garments

    SBC: LYNNTECH INC.            Topic: CBD06108

    While zero-based tolerance protective clothing is suitable for first responders, it provides an unnecessary level of protection for first receivers who are exposed to a considerably reduced threat. The use of zero-based tolerance garments by first receivers is particularly problematic since they often work in the same garments for an extended period of time. Consequently, the unique needs of fir ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  4. Omni-Directional, Wind and Water Tolerant Inlet for the DFU

    SBC: ENERTECHNIX, INC.            Topic: CBD07116

    The current DFU inlet exhibits poor aerosol sampling efficiency at high wind speeds. This project will develop an improved inlet with very high sampling efficiency for 1 to 20 micron particles at wind speeds up to 30 mph independent of wind direction. The project is focused on the DFU, but our Aerodynamic Next Generation Inlet (ANGI) will be beneficial for any high volume aerosol sampling applicat ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. New DNA/RNA Sequencer for Rapid Assessment of Exposure to Infectious Agents

    SBC: LYNNTECH INC.            Topic: N/A

    "The importance of DNA/RNA-based assays for detection of biological warfare agents, identification of diseases, genome sequencing, and environmental control is enormous and will inevitably increase. The challenge is the development of low cost andportable methods for sequencing DNA and RNA extracted from surfaces and fluids, to recognize exposure to biowarfare agents. All the conventional techn ...

    SBIR Phase II 2002 Department of DefenseOffice for Chemical and Biological Defense
  6. Miniaturized Sample Preparation Module

    SBC: MesoSystems Technology, Inc.            Topic: N/A

    "The detection of biological materials used by terrorists and in warfare has become a high priority throughout the world. Thus, the need for rapid microbiological monitoring of water, air, surfaces, and food for the military has accelerated development offaster diagnostic technologies. Recent advances in detection methods based on PCR amplification of the genetic material, antigen and antibody p ...

    SBIR Phase II 2002 Department of DefenseOffice for Chemical and Biological Defense
  7. Imidazenil: A Protective Agent Against Chemical Warfare Agents induced Status Epilepticus

    SBC: NEUPHARMA, INC.            Topic: CBD05116

    The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  8. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  9. Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System

    SBC: LYNNTECH INC.            Topic: CBD08101

    The measurement of biochemical changes within the human body can provide a means to monitor a person’s physiological health. Many of the biochemicals that provide a snapshot of a person’s health are proteins. The challenge with measuring proteins is the existence of approximately ten orders of magnitude difference in concentration between the most abundant proteins in blood and those typically ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Aptamer-Enhanced Biorecognition Reagent System

    SBC: OMNISITE BIODIAGNOSTICS, INC.            Topic: N/A

    "OmniSite BioDiagnostics, Inc. (OmniSite) proposes to develop DNA Aptamers to Bacillus anthracis (nonpathogenic Sterne strain) spores and staphylococcal enterotoxin B (SEB) by the SELEX process. Aptamers are less expensive than antibodies to produce, do notrequire animal hosts for production, can be protected from nucleases, and used in a variety of assay formats to replace antibodies. In Phase I, ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
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