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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Aerosol Collector Technology
SBC: ZAROMB RESEARCH CORP Topic: CBD03107Efficient aerosol collectors are needed to help detect very low concentrations of lethal pathogens, such as Anthrax bacilli, in air. Although existing wetted wall cyclone aerosol collectors can remove a substantial fraction of particulates from a large vo
SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense -
Automated Rational Design of Antibodies
SBC: BIOREN Topic: CBD04105Bioren's technology provides an efficient, automated, in vitro system to generate and optimize antibodies and antibody fragments through a rational, hypothesis-driven approach. Bioren's patented technology is based on synthetic oligonucleotide chemistry to create defined antibody mutations. Hypotheses regarding the impact of a specific amino acid's side-chain chemistry within the antigen binding ...
SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense -
Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents
SBC: LYNNTECH INC. Topic: CBD08107Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Botulinum Toxin Plantibodies
SBC: Planet Biotechnology Incorporated Topic: CBD03103The primary goals of this Phase II application are to successfully manufacture pilot-scale quantities of neutralizing anti-botulinum toxin antibodies in plants, and to complete preclinical studies with these antibodies. Our collaborator, Dr. James D. Mar
SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense -
Carbon Nanotube-Based Filters for Aerosol Sample Collection
SBC: AGAVE BIOSYSTEMS INC. Topic: CBD07111Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...
SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense -
Collective Protection for Military Working Dogs
SBC: AGAVE BIOSYSTEMS INC. Topic: CBD08103Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Combined Dielectrophoretic Microfluidic System
SBC: Physical Optics Corporation Topic: CBD08101To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two-dimensio ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Computer-Assisted Strain Construction And Development Engineering (CASCADE)
SBC: GENOMATICA, INC. Topic: CBD06107The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...
SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense -
Computer-Assisted Strain Construction And Development Engineering (CASCADE)
SBC: QUANTUM INTELLIGENCE, INC. Topic: CBD06107This proposal is to respond Army CBD SBIR Phase II invitation for “Computer-Assisted Strain Construction and Development Engineering (CASCADE)”. Our approach is to apply a machine learning system together with publicly available data and private collaboration data for discovering the predictive relations between genomic fingerprints of an organism and its metabolic capabilities, and then use t ...
SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense -
Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological
SBC: CFD RESEARCH CORPORATION Topic: CBD07114The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...
SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense