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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Low-Cost, High-Performance Colloidal Quantum Dot LWIR FPA for Hyperspectral Imaging

    SBC: SIVANANTHAN LABORATORIES, INC.            Topic: CBD13105

    The primary goal of this proposed work is to develop a long wave infrared (LWIR) colloidal quantum dot (CQD)-based focal plane array (FPA) in order to significantly reduce the cost of LWIR hyperspectral imagers. In order to realize this goal, it will first be necessary to successfully fabricate and demonstrate the performance of novel LWIR HgTe CQD detector arrays. This will be accomplished thro ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  2. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD Research Corporation            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  3. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD Research Corporation            Topic: OSD11H14

    Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  4. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD Research Corporation            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  5. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: Lynntech Inc.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Cloud-Based Predictive Analytics for TBI/PTSD

    SBC: VCRSOFT LLC            Topic: DHP12005

    Existing clinical decision support systems (CDSS) for TBI/PTSD are not well integrated with clinical pathways, terminologies/codes, and/or electronic medical records. Further, these CDSS do not leverage the latest computing technologies such as cloud computing, speech recognition, mobile computing and NLP. In particular, latest advances in machine learning / predictive analytics are not utilized. ...

    SBIR Phase I 2013 Department of DefenseDefense Health Program
  8. Cohort Development and Analysis Toolkit (CDAT)

    SBC: KNOWLEDGE BASED SYSTEMS, INC.            Topic: DHP12006

    We propose to design and develop a Cohort Development and Analysis Toolkit (CDAT) that will assist clinicians, practice administrators and public health professionals in comparing the effectiveness of different clinical practices, including preventive and treatment modalities. The overall goal of CDAT is to facilitate comparative effectiveness research and evidence-based practice without the nece ...

    SBIR Phase I 2013 Department of DefenseDefense Health Program
  9. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Detection of Liquid Contaminants on Surfaces Using Hyperspectral Imaging

    SBC: EPIR TECHNOLOGIES INC            Topic: CBD12104

    Quick detection of Chemical/Biological (CB) agents in the field can provide critical reconnaissance and contamination avoidance. CB agents pose a serious threat to both civilian and military sectors, and present techniques rely on dangerous collection methods, active measurement through external infrared (IR) sources, and/or are time-consuming. EPIR proposes to provide critically needed improvemen ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense

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