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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Hand-Held Non-Contact Burn Triage System Utilizing Visible and Thermographic Imaging in 3D.

    SBC: SIVANANTHAN LABORATORIES, INC.            Topic: DHP16C005

    Thermal injuries are common in all modern military conflicts and care given shortly after a severe burn is critical to its treatment and recovery. Triage for burn injuries is primarily separated into superficial burns which will heal naturally, and deep burns which require surgery. In far-forward environments non-expert combat medics must make burn triage decisions without the aid of lab equipment ...

    STTR Phase I 2017 Department of DefenseDefense Health Program
  2. A Human Body Model for Computational Assessment of Blast Injury and Protection

    SBC: CFD Research Corporation            Topic: DHP13010

    There is a great need to establish an integrated framework for comprehensive analysis of blast injury events, evaluation of protective equipment and assessment of injury probabilities. Presently, such tool does not exist. The initial Phase II project has developed, partially validated and demonstrated a multiscale simulation framework integrating several blast injury biomechanics modeling componen ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  3. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: Lynntech Inc.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  5. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Dynamic Warfighter Avatars with Complete Articulated Anatomy

    SBC: CFD Research Corporation            Topic: DHA17003

    Complete human anatomy avatars have a broad future role in advanced training environments, providing, for example, medically correct immersive experiences, performance-related physiological modeling studies, and in simulations for the purpose of designing protective armor. USARIEM have created individualized avatars as 3-D tetrahedral Finite Element (FE) meshes with full labeled anatomy, fitted to ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  9. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD Research Corporation            Topic: CBD152003

    Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  10. Field portable Coliform Bacteria and Escherichia Coli RNA expression LAMP-OSD detection system

    SBC: Fabrico Technology, Inc.            Topic: DHA17004

    Fabrico Technology and Professor Andrew Ellington of the University of Texas at Austin, proposes to develop an in-field detection platform based on a novel variation of loop-mediated isothermal amplification (LAMP). The proposed reaction works by utilizing a patent pending oligonucleotide strand displacing (OSD) probe which functions for LAMP in much the same way as a TaqMan probe functions for q ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program

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