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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Bio-Inspired Dry Fibrillar Adhesives for Enhanced Sealing of Respiratory Protective Masks

    SBC: NANOGRIPTECH            Topic: CBD09102

    NanoGripTech LLC proposes to develop repeatable skin adhesives using technology inspired by the feet of geckos and insects. These adhesives will be integrated into full facemask respirators to reduce or replace head harness straps, which are currently used to hold the facemasks in place. Expected benefits are improved fit, resistance to shifting, improved sealing, and reduced discomfort and tiss ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. CBRN Sensor and Sensor Netting Algorithms

    SBC: MESH INC            Topic: CBD09110

    Being proposed is a way to integrate the inputs from multiple sensors and different types of sensors to produce a map of the chemical threat. This technique weights every input based on type of sensor, minimum detectable level, health and status of each instrument, and time and position errors. The Sensor Netting Algorithm (SNA) will be based on tomography with weighting factors. The output wil ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. CBRN Sensor and Sensor Netting Algorithms

    SBC: Torch Technologies, Inc.            Topic: CBD09110

    information) During Phase I the Torch Technologies developed, demonstrated, and assessed the feasibility of an innovative, real-time multi-layered CW sensor data fusion network capability supporting advanced standoff detection and early warning against CB threats. Torch merged two significant technologies that we developed for the Department of Defense: 1) the ACRES CW multi-sensor data fusion t ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Chemical Warfare Agent (CWA) Lightweight Field-Portable (Hand-Held) Medical Diagnostic Tool

    SBC: RAPID PATHOGEN SCREENING, INC.            Topic: CBD06104

    The U.S. Army Medical Research Acquisition Activity at Fort Detrick, MD awarded an SBIR Phase I contract to Rapid Pathogen Screening, Inc. (RPS) in May 2006. The overall objective of this SBIR topic is to develop a lightweight field-portable (i.e., hand-held) device that fulfills a two-fold purpose as follows: (1) it will detect/identify Chemical Warfare Nerve Agents (CWNAs) of operational conce ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Distributed Thermal Imaging Spectrometer for Force Protection

    SBC: MESH INC            Topic: CBD09108

    This proposal describes how a very low cost hyperspectral imager can be built. The key to the low cost is the use of a commercially available thermal camera based on an uncooled microbolometer as the detecting element. An interferometer is placed in front of the camera to produce the spectrum. Each frame of the camera captures one point of the interferogram, producing a hyperspectral image at 8 ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  10. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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