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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Low-Output High Precision Automated Powder Disseminator

    SBC: ADVANCED MECHANICAL SYSTEMS TECHNOLOGY,            Topic: CBD06101

    This proposal presents a Phase II SBIR project to produce prototypes of the automated high precision, low disperse rate powder disseminator for the US Army, that has been successfully designed and analyzed in the Phase I project. In the development of the sensitive detecting agent, we need to release a precise amount of C&B agents in the controlled detection experiments. At the end of this Phase ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Carbon Nanotube-Based Filters for Aerosol Sample Collection

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD07111

    Aerosols represent one of the more efficient methods to distribute biological and chemical agents throughout the atmosphere. Small aerosol droplets can be readily inhaled and easily penetrate deep into the lungs where they lodge in bronchial alveoli. Within the alveoli, chemical and biological agents can breach epithelial and endothelial cell layers and enter the bloodstream, where they cause da ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  4. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Sustainable Production of Pinfish (Lagodon rhomboides) for the Live Bait Market

    SBC: AQUATIC INNOVATIONS            Topic: N/A

    Recreational saltwater fishing is a major industry in coastal areas of the United States. The U.S. Fish and Wildlife Service estimated that saltwater anglers spent $8.4 billion in 2001 on fishing trips and supplies. In many communities this type of "wildlife tourism" is the lifeblood of the community. It is vital to these communities to have a consistent supply of needed goods for these anglers. T ...

    SBIR Phase I 2008 Department of Agriculture
  7. Association of Honey Bee SNPs with Varroa destructor mite resistance

    SBC: Bee Power, LP            Topic: N/A

    "Honey bee pollination is estimated to contribute over $14 billion annually to agricultural production. Honey bee pollination services in the larger ecosystem are also of vital importance. However, apiculture in the United States is threatened, especially by infestations of exotic parasitic mites. Varroa destructor, in particular, is lethal to many colonies, decimating both feral and managed honey ...

    SBIR Phase I 2007 Department of Agriculture
  8. Rapid enzyme-based assays to detect banned substances in food

    SBC: BIOO SCIENTIFIC CORPORATION            Topic: N/A

    It is important to test the food supply for known toxic or banned substances which can impinge public safety. While a number of high-throughput tests have been developed to screen the food supply for higher molecular weight banned substances, it has been difficult to develop methods to comprehensively screen the food supply for low molecular weight banned substances such as histamine or pentachlor ...

    SBIR Phase I 2008 Department of Agriculture
  9. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Hybrid System for Ultrasound Signal, Spectral, and Image Analyses to Enhance Meat Quality Evaluation in Food Animals

    SBC: BIOTRONICS, INC            Topic: N/A

    Determining meat quality attributes in food animals is essential for genetic selection, sorting, and marketing. Ultrasound techniques have the potential to benefit the swine industry for improvements in both quality and yield measures by non-destructive means. There is a need to continually improve percentage intramuscular fat estimation accuracy and reduced bias, especially before integration of ...

    SBIR Phase I 2008 Department of Agriculture
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