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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a Fire-Resistant, Thermal Barrier Coating with Low-Temperature Flexibility

    SBC: Advanced Materials and Processes            Topic: A08T028

    Advanced Materials and Processes (AMP) can deliver a Thermal Barrier Coating (TBC) with low temperature flexibility. This is possible because of a major breakthrough in hollow clay nanotube technology. Halloysite nanotubes (HNT™) have been shown to increase coating flexibility an order of magnitude by reinforcing the binder at the nanolevel. HNT have been filled with liquid flame retardant (F ...

    STTR Phase I 2008 Department of DefenseArmy
  2. Xenopus Melanophore-Based Toxicity Sensor for Water

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A07T030

    Deployed armed forces often have to rely on water that is produced from decentralized sources, which presents significant difficulties for assuring the water is free of chemical toxicants. Analysis of these water supplies often requires complex instrumentation that is not practical for field use. An innovative alternative is the use of cell-based biosensors that can rapidly assess the general to ...

    STTR Phase I 2007 Department of DefenseArmy
  3. Detection of Explosive Materials Using an Encapsulated Fluorescent Bioprobe

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A06T025

    The use of explosives over the last 100 years has left up to 16,000 military ranges contaminated with highly toxic compounds. A major challenge to the remediation of these ranges is identifying the location of persistent explosives residues. To meet this challenge, Agave BioSystems in collaboration with Universities Space Research Agency (USRA) is developing an encapsulated fluorescent bioprobe ...

    STTR Phase II 2007 Department of DefenseArmy
  4. Ante-Mortem TSE Diagnosis by Electric Cell-Substrate Impedance Sensing

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T035

    Transmissible spongiform encephalopathies (TSE) are responsible for fatal neurodegenerative diseases in humans, cattle, and sheep/goats. As TSEs can take many months and even years to present clinical symptoms, it is critical for food and contact safety to diagnose the disease at the earliest possible time point. A cell culture based system can offer the sensitivity and specificity required for a ...

    STTR Phase I 2008 Department of DefenseArmy
  5. Xenopus Melanophore-Based Toxicity Sensor for Water

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A07T030

    Deployed armed forces often have to rely on water that is produced from decentralized sources, which presents significant difficulties for assuring the water is free of chemical toxicants. Analysis of these water supplies often requires complex instrumentation that is not practical for field use. An innovative alternative is the use of cell-based biosensors that can rapidly assess the general toxi ...

    STTR Phase II 2008 Department of DefenseArmy
  6. Cell-based High Throughput Screening of Compounds Improving Mitochondrial Energetics

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T006

    Improving age-related decrease in cognitive and physical capabilities has tremendous potential for the civilian population and military personnel, including prolonged aptitude of highly-trained military personnel and lowering of healthcare costs. Mitochondria, the organelle responsible for energy production in eukaryotic cells, are directly involved in programmed cell death and associated to the ...

    STTR Phase I 2008 Department of DefenseArmy
  7. Ionic Liquid Monopropellant Based Gas Generator

    SBC: STREAMLINE AUTOMATION LLC            Topic: A08T022

    Energetic ionic liquids (EIL) represent a new, and potentially revolutionary development in propulsion chemistry. These salts, with unique attributes of surface tension, vapor pressure, thermal stability, and reactivity are leading candidates for low-toxicity, reduced hazard replacements of conventional (hydrazine based) monopropellants. C3 Propulsion, in collaboration with the Center for Green Ma ...

    STTR Phase I 2008 Department of DefenseArmy
  8. A High Throughput Screening Approach Enabling Sustainable Discovery of Novel Lead Compounds from Natural Product Extracts

    SBC: CFD RESEARCH CORPORATION            Topic: A07T034

    We propose the development of a high-throughput screening platform to facilitate the discovery of lead compounds from natural product extracts (NPEs). The proposed effort encompasses (a) utilization of NPEs from novel sources (cave organisms) with rich chemical diversity, (b) development of assays for specifically identified malaria targets, and (c) development of data management and analysis tool ...

    STTR Phase I 2007 Department of DefenseArmy
  9. A Systems Biology Approach to Enable Safe Administration of Mefloquine

    SBC: CFD RESEARCH CORPORATION            Topic: A06T034

    Mefloquine is known to cause adverse neurological effects, possibly attributable to single nucleotide polymorphisms (SNPs). Our objective is to develop a genetic screen capable of determining the susceptibility of an individual to Mefloquine neurotoxicity. In Phase I, transcriptional profiling of primary neurons exposed to Mefloquine was used to construct an intracellular pathway model to explain ...

    STTR Phase II 2007 Department of DefenseArmy
  10. High-Fidelity Modeling Tools for Bone Conduction Communication Systems

    SBC: CFD RESEARCH CORPORATION            Topic: A06T033

    Warfighters increasingly rely on radio communication equipment to ensure safety, mission effectiveness, and situational awareness. Current military communication gear involves headphones and acoustic microphones. Unfortunately, headphones cover the ears and deteriorate detection and localization of ambient sounds that may be important for tactical situations. An alternative to air conduction is bo ...

    STTR Phase II 2007 Department of DefenseArmy
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