Award Data

Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

The overall objective of the proposed research is to design, develop and demonstrate fluidic actuator arrays for aerodynamic separation control and drag reduction. These actuators are based on a compact design of low mass-flow fluidic oscillators that produce high frequency (1-5 kHz) oscillating or pulsing jets. Our preliminary experiments on separation control over trailing edge flaps, cavity to ...

Orion requires a rendezvous and docking sensor to provide relative navigation information during proximity operations and docking. In order to dock, the sensor must provide full six degree of freedom (6 DOF) relative position and relative attitude information at a rate sufficient for the rendezvous spacecraft guidance system to robustly control the docking maneuver. Orion faces critical weight iss ...

Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

This proposal describes the preliminary development of passive wireless surface acoustic wave (SAW) based humidity sensors for NASA application to distributed humidity monitoring systems. SAW devices are a platform technology for passive wireless sensing of numerous possible measurands. SAW devices have been demonstrated as passive wireless temperature sensors in NASA contracts NNK04OA28C and NN ...

The objective of this work is to develop a low cost 6 DOF body tracking system to monitor the orientations of an occupants and pedestrians as well as vehicle kinematics in vehicular impact tests. This tracker system can be standalone or part of a subsystem that can communicate with other trackers and external computer via serial, USB and/or Bluetooth interface. The proposed tracker coined Body O ...

We will develop an efficient tool for formal verification of PowerPC 750 executables. The PowerPC 750 architecture is used in the radiation-hardened RAD750 flight-control computers that are utilized in many space missions. The resulting tool will be capable of formally checking: 1) the equivalence of two instruction sequences; and 2) properties of a given instruction sequence. The tool will automa ...

Balcones Technologies, proposes to adapt actively controlled suspension technology developed for high performance off-road vehicles to address NASA's requirement for Active Vibration Control for Ground Support Equipment (GSE). This innovative approach to meeting NASA needs exploits approximately $23M of highly successful R&D since 1993 at the University of Texas Center for Electromechanics (CEM) ...

The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...