Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Development of a Fire-Resistant, Thermal Barrier Coating with Low-Temperature Flexibility

    SBC: Advanced Materials and Processes            Topic: A08T028

    Advanced Materials and Processes (AMP) can deliver a Thermal Barrier Coating (TBC) with low temperature flexibility. This is possible because of a major breakthrough in hollow clay nanotube technology. Halloysite nanotubes (HNT™) have been shown to increase coating flexibility an order of magnitude by reinforcing the binder at the nanolevel. HNT have been filled with liquid flame retardant (F ...

    STTR Phase I 2008 Department of DefenseArmy
  3. Cyclops

    SBC: Advanced Optical Systems, Inc            Topic: A08041

    The Army needs smaller and cheaper precision weapon systems. Semi-Active Laser guidance (SAL), invented in the 1960’s at the Army Missile command, is a powerful approach to smart weapons. In the past, SAL seekers used quadrant detectors, narrow field-of-view optics, gimbals, and actuators. While very effective, they are expensive. Several programs are desperate for a low-cost solution. One drivi ...

    SBIR Phase I 2008 Department of DefenseArmy
  4. Branched DNA Diagnostic for Malaria Parasites

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08118

    The key to effective management of malaria is accurate diagnosis that is also rapid. The “gold standard” microscopy is time-consuming and labor-intensive and suffers from retirement of microscopic diagnostic experts and inaccurate slide reading. A field-deployable diagnostic method that is specific for the different malaria parasites and is capable of quickly processing potential patients wo ...

    SBIR Phase I 2008 Department of DefenseArmy
  5. Ante-Mortem TSE Diagnosis by Electric Cell-Substrate Impedance Sensing

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T035

    Transmissible spongiform encephalopathies (TSE) are responsible for fatal neurodegenerative diseases in humans, cattle, and sheep/goats. As TSEs can take many months and even years to present clinical symptoms, it is critical for food and contact safety to diagnose the disease at the earliest possible time point. A cell culture based system can offer the sensitivity and specificity required for a ...

    STTR Phase I 2008 Department of DefenseArmy
  6. Cell-based High Throughput Screening of Compounds Improving Mitochondrial Energetics

    SBC: AGAVE BIOSYSTEMS INC.            Topic: A08T006

    Improving age-related decrease in cognitive and physical capabilities has tremendous potential for the civilian population and military personnel, including prolonged aptitude of highly-trained military personnel and lowering of healthcare costs. Mitochondria, the organelle responsible for energy production in eukaryotic cells, are directly involved in programmed cell death and associated to the ...

    STTR Phase I 2008 Department of DefenseArmy
  7. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  9. Accurate and Reliable Rocket Thruster Technology

    SBC: Analytical Services, Inc.            Topic: A08040

    In this SBIR project, a preliminary design of a highly accurate, highly repeatable impulse thruster will be completed. ASI, together with ATK, proposes to complete the preliminary design in parallel with the development of a comprehensive thruster model in a Monte Carlo environment that will account for every contributor to repeatability in the final product. Using modern uncertainty analysis te ...

    SBIR Phase I 2008 Department of DefenseArmy
  10. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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