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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Oligonucleotide Enzyme Surrogate (OnES)
SBC: Accacia International LLC Topic: CBD08108Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Ribozymes for In Vivo Degradation of G-Nerve Agents
SBC: AGAVE BIOSYSTEMS INC. Topic: CBD08108Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Collective Protection for Military Working Dogs
SBC: AGAVE BIOSYSTEMS INC. Topic: CBD08103Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Multiple Indication Adjuvants
SBC: BIOPROTECTION SYSTEMS CORP. Topic: CBD08105The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Reduction of Motion Side Effects and After Effects
SBC: Biosentient Corp. Topic: N/A"BioSentient Corporation proposes the use of a proven method of non-pharmacologic physiologic self-regulation to delay the onset and decrease the symptoms of motion sickness and mitigate any concomitant cognitive degradation. The method, NASA patentedAutogenic Feedback Training Exercise-- Method & System (AFTE - M&S), has been shown to significantly improve performance on Coriolis Sickness Susce ...
SBIR Phase I 2002 Department of DefenseOffice of the Secretary of Defense -
Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological
SBC: CFD RESEARCH CORPORATION Topic: CBD07114Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...
SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense -
Automated Preferential Display for the Analysis of Gene Expression Profiles
SBC: GENEXPRESS INFORMATICS, INC. Topic: N/A"GeneXpress Informatics, Inc. (GXI) and Dr. James P. Chambers of UTSA propose to develop a revolutionary differential gene display technology, called Preferential Display (PD) which will provide for a simplified, cost-effective method to identify thesegenes for use in discovering gene expression profiles without having any prior knowledge of an organism, tissue or biological samples' genome. The ...
SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense -
Medical Materiel Knowledge Discoverer (MMKD)
SBC: KNOWLEDGE BASED SYSTEMS INC Topic: N/A"Improving responsiveness requires continual innovation, and technology has created the opportunity to use knowledge discovery for innovation and continual improvement in supply chain logistics. DMLSS can use knowledge discovery to increase medicallogistics support effectiveness while reducing costs in two distinct environments: Military Treatment Facilities (MTFs) and deployed theater forces. The ...
SBIR Phase I 2002 Department of DefenseOffice of the Secretary of Defense -
Military Health Data Mining Algorithms Library (M-HDML)
SBC: KNOWLEDGE BASED SYSTEMS INC Topic: N/A"We propose to develop, build, and validate a Military Health Data Mining Algorithms Library (M-HDML), a set of reusable and extendible knowledge analysis software templates that facilitate the medical knowledge discovery process. Apart from delivering"data-driven" knowledge that is useful from a medical diagnostic/prognostic standpoint, the developed infrastructure would ultimately provide plann ...
SBIR Phase I 2002 Department of DefenseOffice of the Secretary of Defense -
Military Health Data Mining Algorithms Library (M-HDML)
SBC: KNOWLEDGE BASED SYSTEMS INC Topic: N/A"We propose to develop, build, and validate a Military Health Data Mining Algorithms Library (M-HDML), a set of reusable and extendible knowledge analysis software templates that facilitate the medical knowledge discovery process. Apart from delivering"data-driven" knowledge that is useful from a medical diagnostic/prognostic standpoint, the developed infrastructure would ultimately provide plann ...
SBIR Phase II 2002 Department of DefenseOffice of the Secretary of Defense