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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Brain Targeting Nanoparticle for Drug Delivery in Traumatic Brain Injury

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: DHA18A001

    There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  2. Point of care, microfluidic, multi-electrode and optical hybrid CBC

    SBC: LYNNTECH INC.            Topic: DHA172008

    Lynntech will design and build a laboratory scale reduced weight, environmentally stable, CBC device which is usable at Role 1 and higher which requires no cold chain storage. The device is specifically intended to be used by medical personnel deployed in Health Response Teams (HRTs) who are not lab technicians and who do not have rapid, reliable access to a hematology lab. To this end, the soluti ...

    SBIR Phase I 2018 Department of DefenseDefense Health Agency
  3. Vestibular Rehabilitation Aid (VestAid)

    SBC: Intelligent Automation, Inc.            Topic: DHA172014

    Service members exposed to blasts have frequent complaints of dizziness Appropriate treatment is critical for many reasons: Service members with complaints of dizziness and imbalance are often unable to perform their duties.This results in slower reaction times, decreased productivity (in the form of lost duty days) and negatively impacts force readiness.An integral part of vestibular rehabilitati ...

    SBIR Phase I 2018 Department of DefenseDefense Health Agency
  4. Injectable Bio-compatible gel composed of iPSC derived NSC for regeneration of brain tissue

    SBC: FABRICO TECHNOLOGY, INC.            Topic: DHA18004

    Stem cell apoptosis occurs when the interaction between the host brain extracellular matrix (ECM) and human induced pluripotent stem cell (iPSC) derived neural stem cell (NSCs) are directly injected into the injured brain regions. Establishment of a connection between ECM and iPSC/NSC could increase cell viability, differentiation, and promote functional recovery of the injured tissue. The critica ...

    SBIR Phase I 2018 Department of DefenseDefense Health Agency
  5. Neural Stem Cell Therapy for Severe Traumatic Brain Injury

    SBC: Neuralstem, Inc.            Topic: DHA18004

    We have identified NSI-566, a stable neural stem cell line, isolated and expanded from a single human fetal spinal cord tissue, as the investigational product for TBI treatment.NSI-566 has been approved by the US FDA as an investigational product for clinical testing in ALS (IND# 13905) and chronic SCI (IND# 14413) which are ongoing.For TBI treatment, we propose to place deposits of NSI-566 into t ...

    SBIR Phase I 2018 Department of DefenseDefense Health Agency
  6. Non-destructive Evaluation of Cellular Cultures

    SBC: NOKOMIS INC            Topic: DHA18006

    Nokomis proposes to develop a real-time microwave spectroscopy device to measure the health and viability of 2D and 3D cell cultures. Utilizing a combination of spectroscopic techniques, Nokomis will utilize existing knowledge of dielectric properties of cell cultures and how they relate to varied parameters of the culture to deliver an in-line, non-destructive measurement device. The proposed wor ...

    SBIR Phase I 2018 Department of DefenseDefense Health Agency
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