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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. A novel therapy for sepsis

    SBC: BIOPOWERTECH            Topic: N/A

    Description: (Provided by Applicant) Sepsis a serious life-threatening condition resulting from a harmful inflammatory reaction of the body due to bacterial infection. The mortality rate of sepsis remains high in intensive care units around the world but therapeutic interventions have been largely unsuccessful. Clearly, there is a great need for inventing efficacious therapeutic drugs to treat pat ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. A Shielded Conditionally Replicative Adenoviral Vector

    SBC: VECTORLOGICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Conditionally replicative adenovirus vectors (CRAds) are novel vectors with utility as virotherapy agents for alternative cancer therapies. These vectors already have established a broad safety record in humans. However, two confounding problems limit efficacy of these drug candidates, the paucity of the native Ad receptor on tumor tissues, and host humoral res ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. A Simulation Tool to Enable Identification of Critical Network Interactions Using

    SBC: CFD RESEARCH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): One of the main challenges in the discovery of intracellular biomarkers and identification of therapeutic targets is the lack of a mechanistic understanding of the complex underlying pathways. The tremendous increase in both the quantity and diversity of cellular data represents a significant challenge to researchers seeking to construct biologically relevant ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. A System for Rapid PCR, Mutation Scanning and Genotyping

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a closed-tube system for rapid PCR, mutation scanning and genotyping that does not require fluorescently-labeled probes. For many genetic diseases, it is difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution for rapid amplification, scanning and genotyping in ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. A System for Rapid PCR, Mutation Scanning and Genotyping

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a closed-tube system for rapid PCR, mutation scanning and genotyping that does not require fluorescently-labeled probes. For many genetic diseases, it is difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution for rapid amplification, scanning and genotyping in ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. A System for Rapid PCR, Mutation Scanning and Genotyping

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a closed-tube system for rapid PCR, mutation scanning and genotyping that does not require fluorescently-labeled probes. For many genetic diseases, it is difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution for rapid amplification, scanning and genotyping in ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. A System for Rapid PCR, Mutation Scanning and Genotyping

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to provide a closed-tube system for rapid PCR, mutation scanning and genotyping that does not require fluorescently-labeled probes. For many genetic diseases, it is difficult and expensive to screen for all possible mutations that may cause the disease. We propose a relatively simple solution for rapid amplification, scanning and genotyping in ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. A Test for Salt Sensitivity in People with Essential Hypertension

    SBC: SEQUELA, INCORPORATED            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary: In Phase I we developed a model system and a prototype Salt Sensitivity Assay to establish proof-of-principle . In Phase II we propose the evaluation of the prototype that will quantitatively measure our biomarker in the target population. An ideal biomarker for salt sensitivity would be one that is linked to the underlying cause of ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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