Award Data

The goal of this project is to investigate the feasability of a unique sampling method that will lead to the development of a reagentless infrared (IR) based BW agent detection system. The current JPBDS uses lateral flow immunoassay technology as the final step in detecting bioagents, and has a detection limit of 10^5 spores/ml[ref 1]. Preliminary data from our infrared approach indicates a mini ...

To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two-dimensio ...

Redondo Optics Inc. (ROI), a world leader in engineering and manufacturing of leading-edge nano-materials, optical sensors, fiber and integrated optics, and advanced photonics instrumentation proposes to develop and demonstrate for the first time the concept of an etch-less, deep-UV, fully continuously variable attenuated-phase-shifted mask (ConvaPSMT) technology to enable ultra-high resolution, o ...

To properly measure (and understand) the performance of a standoff detector, properties of the challenge cloud must be known. Meteorological models, such as HPAC and VLSTRACK, have proven to be reasonably good tools for predicting cloud properties. However, a problem with these tools is that they deliver ensemble averages and may not describe a specific cloud to the detail required. The Dugway ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

In this SBIR Phase I effort, Los Gatos Research (LGR) proposes to design, develop and test a novel laser-based gas analyzer optimized for chemical weapon exposure studies based on cavity enhanced absorption in the mid-infrared spectral region. This analyzer will provide sensitive and accurate quantification of several chemical weapons through real-time measurements of high-resolution absorption s ...

Aerius Photonics and partner Ahura Scientific, propose to develop a handheld system, based on Ahura’s successful FirstDefender Raman system, that employs an excitation laser emitting at 980 nm and a low noise InGaAs array based on Aerius’ high performance InGaAs technology. This system will substantially reduce the fluorescence present in CCD-based systems, and unmask otherwise obscured spect ...

To address the CBD need for a real-time measurement system for nonhuman primate and rabbit respiratory tidal volumes suitable for a Class 3 biological safety (BSL-3) cabinet, Physical Optics Corporation (POC) proposes to develop a new Respiratory Function Measurement (RFM) system. This system is based on a piezoelectric transducer that responds to pressure generated by the animal’s thoracic cag ...