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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. 3D Scaffold and Stem Cell Based Bioengineered Skin for Treatment of Cutaneous Vesicant Injury

    SBC: Nomadics, Inc.            Topic: CBD05117

    Vesicants have been used as chemical warfare agents since World War I and are still considered a major class of chemical threat agents both for the military and for homeland security. There are four different vesicating agents: impure sulfur mustard, distilled sulfur mustard, phosgene oxime, and lewisite. Among them, mustard is the most important militarily. The organs most commonly affected by ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. 3D Scaffold and Stem Cell Based Bioengineered Skin for Treatment of Cutaneous Vesicant Injury

    SBC: Nomadics, Inc.            Topic: CBD05117

    In this Phase II project Nomadics will novate our research to a spin-out company Nico Technologies. Nomadics will remain a subcontractor during this transition. The team proposes a new treatment for injuries from mustard gas based on biodegradable inverted colloidal crystal scaffolds impregnated with stem cells. Phase I results demonstrated excellent performance of these scaffolds for different ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Autonomous, Unattended, Reagentless Biological Agent Detector

    SBC: Orono Spectral Solutions Inc.            Topic: CBD05111

    The goal of this project is to investigate the feasability of a unique sampling method that will lead to the development of a reagentless infrared (IR) based BW agent detection system. The current JPBDS uses lateral flow immunoassay technology as the final step in detecting bioagents, and has a detection limit of 10^5 spores/ml[ref 1]. Preliminary data from our infrared approach indicates a mini ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. Critical Data Processing for Chemical Warfare Simulant Field Testing- Advanced Data Fusion

    SBC: TORCH TECHNOLOGIES INC            Topic: CBD05110

    To properly measure (and understand) the performance of a standoff detector, properties of the challenge cloud must be known. Meteorological models, such as HPAC and VLSTRACK, have proven to be reasonably good tools for predicting cloud properties. However, a problem with these tools is that they deliver ensemble averages and may not describe a specific cloud to the detail required. The Dugway ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  5. CW Indicating Chromophore for Decontamination Operations

    SBC: Nomadics, Inc.            Topic: CBD04103

    In Phase I, Nomadics demonstrated that a novel chemical weapon indicating chromophore (CWIC) developed by Professor Tim Swager at MIT will allow equipment to be quickly and easily examined to show any areas of contamination, making targeted decontamination manageable. When exposed to CW agent simulants, CWICs react to become fluorescent under UV stimulation. In the first phase, we implemented a s ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Realtime Detection And Identification Of Airborne Microorganisms Using Infrared Spectroscopy

    SBC: Orono Spectral Solutions Inc.            Topic: CBD06102

    The goal of this Phase II project is to develop an automated detector system for real-time detection of aerosolized biowarfare agents. Our proposed detection system utilizes Fourier Transform Infrared (FTIR) spectroscopy as the agent identifier, where the main advantages of this approach are that it is reagentless, operates in complex air environments, and provides fast detection, high sensitivit ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense

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