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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Autonomous, Unattended, Reagentless Biological Agent Detector

    SBC: Orono Spectral Solutions Inc.            Topic: CBD05111

    The goal of this project is to investigate the feasability of a unique sampling method that will lead to the development of a reagentless infrared (IR) based BW agent detection system. The current JPBDS uses lateral flow immunoassay technology as the final step in detecting bioagents, and has a detection limit of 10^5 spores/ml[ref 1]. Preliminary data from our infrared approach indicates a mini ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Camouflaged liposome construct for efficient drug delivery across the blood-brain barrier

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD08107

    A major obstacle to non-invasive treatment of brain injury and disease is the blood-brain barrier (BBB), which prevents many intravenously injected therapeutics from being taken into the brain. In this program, Luna Innovations and Virginia Tech propose to develop a novel liposome-based delivery system capable of delivering any of a variety of neuroprotective agents of use against organophosphate ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Critical Data Processing for Chemical Warfare Simulant Field Testing- Advanced Data Fusion

    SBC: TORCH TECHNOLOGIES INC            Topic: CBD05110

    To properly measure (and understand) the performance of a standoff detector, properties of the challenge cloud must be known. Meteorological models, such as HPAC and VLSTRACK, have proven to be reasonably good tools for predicting cloud properties. However, a problem with these tools is that they deliver ensemble averages and may not describe a specific cloud to the detail required. The Dugway ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Generic Adsorptive Carbon Residual Life Indicator

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD07103

    Carbon based filtration technologies have several known modes of degradation and failure including adsorption of chemical contaminants, adsorption of environmental pollutants and operational interferents, repeated moisture condensation, and moisture vapor adsorption. In unknown hazardous environments, the ultimate End-of-Service-Life Indicator (ESLI)/Residual Life Indicator (RLI) for critical Ind ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  7. Generic Adsorptive Carbon Residual Life Indicator

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD07103

    Generic residual life indicator technology developed under PI effort will be matured through reduction of COTS items used in the breadboard design to a miniaturized brassboard system capable of detecting agent saturation front migration through a sorbent. The capability of this brassboard system to detect representative agents from several classes will be demonstrated along with the ability to pr ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Realtime Detection And Identification Of Airborne Microorganisms Using Infrared Spectroscopy

    SBC: Orono Spectral Solutions Inc.            Topic: CBD06102

    The goal of this Phase II project is to develop an automated detector system for real-time detection of aerosolized biowarfare agents. Our proposed detection system utilizes Fourier Transform Infrared (FTIR) spectroscopy as the agent identifier, where the main advantages of this approach are that it is reagentless, operates in complex air environments, and provides fast detection, high sensitivit ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  9. Self Sanitizing Thin Films Using Discrete Toxicant/Germinant Surface Features

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD07110

    With global terrorism on the rise, there is an increasing need to develop self sanitizing surfaces and surface treatments with maximum potential to kill biological organisms in order to minimize hazard to human health. Luna Innovations proposes the creation of self sanitizing films that can be used as protective overcoats to destroy bacterial quickly and prevent human infection without the need fo ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  10. Spectroscopic Imaging Technology for THz Biosensor Integrated with a Lab-on-Chip Platform

    SBC: VIBRATESS            Topic: CBD07104

    In this Phase I SBIR project we propose a new imaging mechanism for sub-wavelength THz spectroscopy based on a very strong enhancement of electromagnetic field of the THz radiation at the edges of periodic semiconductor structure. Our recent theoretical study showed THz radiation power enhancement ~1100 with the half power width around the slot edges ~500 nm. Such strongly enhanced local electroma ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense

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