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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. 3D Scaffold and Stem Cell Based Bioengineered Skin for Treatment of Cutaneous Vesicant Injury

    SBC: Nomadics, Inc.            Topic: CBD05117

    Vesicants have been used as chemical warfare agents since World War I and are still considered a major class of chemical threat agents both for the military and for homeland security. There are four different vesicating agents: impure sulfur mustard, distilled sulfur mustard, phosgene oxime, and lewisite. Among them, mustard is the most important militarily. The organs most commonly affected by ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. 3D Scaffold and Stem Cell Based Bioengineered Skin for Treatment of Cutaneous Vesicant Injury

    SBC: Nomadics, Inc.            Topic: CBD05117

    In this Phase II project Nomadics will novate our research to a spin-out company Nico Technologies. Nomadics will remain a subcontractor during this transition. The team proposes a new treatment for injuries from mustard gas based on biodegradable inverted colloidal crystal scaffolds impregnated with stem cells. Phase I results demonstrated excellent performance of these scaffolds for different ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  3. Aerogel-Based Chemical and Biological Protective Fabrics.

    SBC: ASPEN AEROGELS, INC.            Topic: CBD05123

    The Department of Defense has identified the need to develop aerogel-based Chemical/Biological (CB) protective fabrics with good moisture vapor transmission for use in garment and collective protection systems. Aspen Aerogels proposes to develop aerogel-coated fabrics as a novel protection material against chemical and biological warfare agents. The aerogel component will be based on silica and ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  5. Automated Objective Speech Intelligibility Assessment System

    SBC: LI Creative Technologies Inc.            Topic: CBD07106

    Based on our successful experiences in automatic speech recognition, we propose a unique and promising solution for the automated objective speech intelligibility assessment system. It consists of a pair of head and torso simulators placed at the same distance as typical face-to-face communication, a power amplifier, a laptop computer, a speech recognizer, and console software. The simulator has a ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  6. Automated Objective Speech Intelligibility Assessment System

    SBC: LI Creative Technologies Inc.            Topic: CBD07106

    Based on the success of our Phase I feasibility research, we propose to continue the project for the automated objective speech intelligibility assessment system. It consists of a pair of head and torso simulators placed at the same distance as typical face-to-face communication, a power amplifier, a laptop computer, a speech recognizer, and console software. The simulator has acoustic properties ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Autonomous, Unattended, Reagentless Biological Agent Detector

    SBC: Orono Spectral Solutions Inc.            Topic: CBD05111

    The goal of this project is to investigate the feasability of a unique sampling method that will lead to the development of a reagentless infrared (IR) based BW agent detection system. The current JPBDS uses lateral flow immunoassay technology as the final step in detecting bioagents, and has a detection limit of 10^5 spores/ml[ref 1]. Preliminary data from our infrared approach indicates a mini ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Biological Aerosol Agent Fate Model

    SBC: MICROBIAL AEROSOL RESEARCH LABORATORY, LLC            Topic: CBD05121

    It is proposed to formulate an equation(s) to describe the (A) evaporation and (B) death rates of aerosolized bacteria in their spent culture fluid droplets. This formulation will account for effects of atmospheric temperature, relative humidity, solar radiation, droplet solute concentration, and droplet size effects perhaps including effects of solute-particle (i.e,, bacteria) concentration and p ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Blending of Aircraft Washing/Cleaning Detergents and Chemical/Biological (CB) Warfare Agent Decontaminants for a Dual-Use Application

    SBC: MATERIALS ENGINEERING AND TECHNICAL SUPPORT SERVICES CORP.            Topic: CBD05115

    Under the current SBIR solicitation, the DoD is interested in the development of novel decontaminant solutions based on existing aircraft approved fluids (e.g., cleaning or deicing fluids), and application methods that will be compatible with the Transportable Decontamination System (TDS). The aircraft decontaminating solution should be capable of detoxifying chemical warfare (CW) agents, Non-Tra ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: Lynntech Inc.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense

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