Award Data

This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel manufacturing method to produce high-accuracy, optical encoders. Encoders are sensors that measure position, either linear or angular, and convert it into an electronic signal. Modern automation and robotics systems heavily rely on encoders for precision positioning and motion control. The global encoder market ...

Abstract For about 175,000 leg and hip fractures each year, the best treatment is for an orthopaedic surgeon to implant a stiff metal rod, or intramedullary (IM) nail, through the center of the bone and fix the nail to the bone with screws (distal locking). Distal locking can be difficult and time-consuming step and presents two major challenges. First, the procedure uses C-arm fluoroscopy for gui ...

Abstract Hyperphosphatemic familial tumoral calcinosis (hfTC) is a disease in which patients cannot produce the bioactive form of the hormone Fibroblast growth factor-23 (FGF23), which is secreted by osteocytes to rid the body of phosphate by acting on the kidney. hfTC is characterized by markedly elevated serum phosphate (Pi) which causes large intramuscular calcifications to develop. The calcifi ...

The STRATFI Earth 616 project will create a proof of concept secure Distributed Ledger Technology (DLT) based environment to provide near real-time visibility and traceability, along with associated securing of digital assets, for parts and data from an i

Magnesium metal, sometimes referred to as the “Green Metal” is important for defense and industrial use, as it is the lightest of all the structural and engineering metals. Magnesium also has superior mechanical properties such as high dampening capacity, heat dissipation, and shock absorbing capacity. Magnesium is 100% recyclable. Due to these factors, magnesium metal is in high demand in the ...

In this Phase IIB SBIR project for Alzheimer’s disease (AD) drug development, Neurodon LLC proposes to conduct preclinical development and IND-enabling activities on our novel, orally available lead and backup compounds that, in our preceding Phase II project, showed neuroprotection and beneficial effects on learning and memory in a transgenic model of AD. Despite the enormity of AD as a nationa ...

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PROJECT SUMMARY Thoracic surgery (TS), especially pneumonectomy, lobectomy and segmentectomy, are common and very painful surgeries for lung lesions with high incidence of uncontrolled acute surgical pain, chronic post- thoracotomy pain and excessive opioid use. Those with poorly controlled acute surgical pain are at risk for chronic post-surgical pain (CPSP), long-term opioid use and opioid addic ...

This direct to Phase II program is needed to take the commercial Migrating Combustion Chamber (MCC) FE-120 baseline engine and complete the development, design improvements and testing that is required for integration into a Group 1 SUAS, like the RQ-20 P

The United States Air Force (USAF) aims to enhance the energy efficiency and readiness of the C-17 Globemaster III through the application of AeroCore's advanced technologies. These technologies, including Nucleated Foam Technology and On-Wing Restoration