Award Data

We will develop a highly integrated flight planning, centralized data, enriched information, mission reporting, and global connectivity platform called SD Pro. SD Pro from Satcom Direct will create Advanced Connectivity through management and forecasting

Satcom Direct is the leading provider of aeronautical satellite connectivity services to US Government, Military, DoD, and federal agencies who depend on reliable, global communications The new Satcom Direct ESA Flat Panel Antena was developed for busines

1 Abstract2 Bold Type is developing the “SenseWand”, a wireless pelvic floor diagnostic system (device and app)3 to evaluate pelvic floor muscle health using electrical impedance myography (EIM). PFDs are complex4 conditions (e.g. pelvic organ prolapse, stress urinary incontinence, high tone pelvic floor dysfunction) that impact5 millions of women worldwide. It is estimated that PFDs will affe ...

PROJECT SUMMARY/ABSTRACT The MYC family proteins are comprised of three paralogs termed c-myc, N-myc, and L-myc. The MYC proteins play a fundamental role in cell proliferation and oncogenesis by regulating cellular processes such as gene transcription, protein translation, cell cycle progression, and cell death. While N-myc and L-myc drive oncogenesis in a small number of cancer types, the require ...

ABSTRACT Pulmonary arterial hypertension (PAH) is a fatal disease (without curative therapies) that is critically influenced by dysregulated inflammatory pathways. This A1 R42 Fast Track STTR application focuses on eNAMPT (extra- cellular nicotinamide phosphoribosyltransferase) as a novel, highly attractive PAH target. Aqualung Therapeutics has developed a humanized eNAMPT-neutralizing mAb, ALT-10 ...

In summary, the effort will improve City Labs’ tritium power source to provide long-term power for small space satellites. The stacking methodology for robust assembly of devices with multiple layers of metal hydride and semiconductor material will be enhanced in this project. The effort will also result in an adequate helium diffusion mechanism in the electronic package which will enable the us ...

Prioritization Engine for Collection Management (ProCOM) is an algorithmic approach for automated collection management across PAI and other sources, that will prioritize PAI, and other non-traditional intelligence collection based upon a representation o

Technical Abstract (Limit to 3000 characters with no classified or proprietary information): The proposed effort applies living intelligence and object-based production concepts already in use in the Air Force to create live documents that describe an acq

ABSTRACT The serious unmet need to address the excessive mortality observed in patients with Acute Respiratory Distress Syndrome (ARDS) has been brought sharply into focus by the current COVID-19 pandemic. In this R-44 application, Aqualung Therapeutics will address this therapeutic gap by utilizing a novel, humanized monoclonal antibody, ALT-100 mAb, which binds/neutralizes a novel ARDS target, e ...

The objective of this proposal is to examine a novel technique called improved Synchronization Modulation Electric Field (i-SMEF) in the protection of donor hearts and improvement of transplanted graft functions. We will apply the i-SMEF on donor hearts during static cold storage and evaluate the transplanted graft function following heart transplantation in mice.Heart transplantation (HTx) remain ...